exam 3 part 2 wrksht 1 - receptorcell. For the above...

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Describe the two different ways that enzyme-linked receptors can be activated. Outline the MAP kinase pathway downstream of rTKs. What are the targets of this pathway?
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What pathways control the release of Ca++ in cells. The total calcium in cells is relatively high,where is it sequested so the normal free calcium concentration is low and its release can be controlled. Describe the function of each of the following domains: SH2, SH3, PH.
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Different receptors can stimulate different subsets of possible rTK pathways, what regulates the specificity? Signal transduction pathways can lead to both short term and long term changes in the functions of the cell. Briefly describe (no more than 1-2 sentences) three types of short-term changes and how they are regulated.
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Outline the signal transduction pathway that leads to depolarization of an olfactory
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Unformatted text preview: receptorcell. For the above olfactory pathway, outline the effects of the following drugs and determinewhether the sensitivity of the sense of smell would be enhanced or decreased A.) GTP-_ S B.)cholera toxin C.) a drug that prevents the re-association of the heterotrimeric G-proteins D.) a PKA inhibitor E.) a phospholipase C inhibitor F.) a PDE inhibitor G.) a calcium chelator Outline the signaling events that are required for a neutrophil to respond to N-formyl peptides with actin polymerization. CaM-Kinase II has been described as a molecular memory device. Describe in words or diagram how this molecule can remember that is was exposed to Ca++ after the Cs++ signal has disappeared, and what has to happen to the molecule to make it forget....
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This note was uploaded on 04/06/2008 for the course MCB 410 taught by Professor Ward during the Spring '08 term at University of Arizona- Tucson.

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exam 3 part 2 wrksht 1 - receptorcell. For the above...

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