BrighamLecture

BrighamLecture - Predictive Health Predictive Health The...

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Unformatted text preview: Predictive Health Predictive Health The Imminent Revolution in Healthcare Kenneth L. Brigham, MD Associate Vice President, Predictive Health Woodruff Health Sciences Center Emory University Calvin Haney Calvin Haney 1968 Why Will the US Health Care System Why Will the US Health Care System Change? Change? Cost Impact Access Efficiency Developing science and technology Social and political pressure Total Health Care Expenditures in 8 Developed Total Health Care Expenditures in 8 Developed Countries Countries Cost Cost US JAP FRA ITA AUS SWE GER BRIT 6 7 8 9 10 11 12 13 14 15 Health care expense (%GDP) Life Expectancy in 8 Developed Countries Life Expectancy in 8 Developed Countries Impact Impact US JAP FRA ITA AUS SWE GER BRIT 79 80 81 82 83 84 85 Life expectancy (yrs) E . N o l t e a n d C . M . M c K e e , H e a l t h A f f a i r s , J a n u a r y / F e b r u a r y 2 8 , 2 7 ( 1 ) : 5 8 7 1 Science and Technology Science and Technology High throughput science Metabolomics Genomics Proteomics Computational biology Systems biology Bioinformatics Molecular imaging Regenerative science Generic predictors Social and Political Pressure Social and Political Pressure Increasing media attention Access to health care a major issue Health insurance costs to industry Changing politics The economic crisis Calvin Haney Calvin Haney 2009 Predictive Health Predictive Health the concept Predictive Health Predictive Health Definition Definition Predictive Health anticipates the course of an individuals health status, based on leading edge science and technology, and prescribes interventions that proactively optimize wellness This revolutionary approach will move from a reactive disease focused system to a pro active health focused system; disease becomes a medical failure The Health/Disease Continuum The Health/Disease Continuum Normal Low risk Normal High risk Pre disease Early disease Late disease Predictive Health Contemporary Medicine H E A L T H D I S E A S E health is a state of complete physical, health is a state of complete physical, mental and social well-being and not merely mental and social well-being and not merely the absence of disease or infirmity the absence of disease or infirmity World Health Organization 1948 Determinants of Health Environment Genetics Behavior Epigenetics Epigenetics-Based Therapy Epigenetics-Based Therapy A Kinky Mouse Tale A Kinky Mouse Tale Determinants of Health Environment Genetics Behavior Oxidative Stress Inflammatory Phenotype Regenerative health Other Generic Pathways Immune function generic predictors Predictive Health and Public Health...
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BrighamLecture - Predictive Health Predictive Health The...

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