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Unformatted text preview: The bond is strained by three negative charges in close proximity. The released phosphate is stabilized by resonance. 4. Describe two ways in which the hydrolysis of ATP can be “used” to do biochemical work. (2 points) The hydrolysis can lead to conformational changes in a protein (eg, myosin). Also, the gamma phosphate can be transferred onto a substrate and the hydrolysis of that phosphate can provide a better leaving group for the reaction. 5. Why is hydrolysis of acetyl-CoA into acetate and CoA an energetically favorable reaction? (2 points) The product, acetate is stabilized by resonance . 6. Draw the intermediate in the isomerization reaction below. (3 points) Deprotonation of C1 and protonation of the carbonyl oxygen give the C=C double alcohol intermediate. 7. Circle the atom that is reduced during the following reaction. (2 points) Biochemistry 309, Winter 2010 20 points...
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- Winter '10
- Adenosine triphosphate