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Unformatted text preview: As a result, the liver synthesizes ketone bodies from the aceyl-CoA for export to the brain and tissues. 5. For a fatty acid having 17 carbons, what are the products of oxidation and how many carbons can be converted into glucose through gluconeogenesis? Explain. (4 points) The oxidation of a 17 carbon fatty acid leads to the production of 7 acetyl-CoAs, and one propionyl-CoA. Acetyl-CoA cannot be used in gluconeogenesis. Propionyl-CoA can be converted to succinyl-CoA and oxaloacetate, which can enter gluconeogenesis. Therefore, 3 carbons of the 17 can be converted into glucose. 6. If a cell has high concentrations of malonyl-CoA, how would this affect fatty acid synthesis vs oxidation? (2 points) Malonyl-CoA inhibits carnitine acyltransferase, which catalyzes the committed step in fatty acid oxidation. This mean that the cell would synthesize fatty acids instead of oxidizing them....
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This note was uploaded on 02/16/2012 for the course BIOL_SCI 309 taught by Professor Somebody during the Winter '10 term at Northwestern.
- Winter '10