20 jan 2010 molbio

20 jan 2010 molbio - Mol bio lecture notes 20 January 2010...

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Mol bio lecture notes 20 January 2010 Bacteria as a model system Bacteria are single celled non-nucleated systems – called prokaryotes Bacteria have been used as a model system to study a number of processes o Recombination o Cell physiology o Cell division and growth o Gene regulation Bacteria are also used as vehicles in molecular cloning experiments Bacteria play a significant role in diseases o Barry J. Marshall and J. Robin Warren win the Nobel Prize for demonstrating that the bacterium Helicobacter pylori is the major cause of peptic ulcers and gastritis. o Antibiotics block bacteria from multiplying o Bacteria have genes that turn on and off; antibiotics turn off transcription, etc Bacteriophage as a model system Bacteriophages are viruses that exclusively infect bacterial cells They have been used to study the following processes o Recombination o Cell attachment o Lytic vs. lysogenic infections (ie chicken pox) o DNA transfer Salvador Luria was awarded the Nobel Prize for his work on phage genetics o IU Biology Professor Viruses play an important role in animal and plant diseases o HIV infections lead to AIDS o Peter Doherty wins Nobel Prize for work on HIV Yeast as a model system Louis Pasteur discovers that yeast are the agent responsible for fermentation
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This note was uploaded on 02/17/2012 for the course BIO 1421 taught by Professor Farr during the Fall '08 term at Texas State.

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20 jan 2010 molbio - Mol bio lecture notes 20 January 2010...

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