27 jan 2010 molbio

27 jan 2010 molbio - Mol bio lecture notes 27 January 2010...

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Mol bio lecture notes 27 January 2010 At what stage of the cell cycle are cells undergoing DNA replication? G and S phase – synthesis phase where DNA is decondensed Is the length of interphase coupled to the rate of replication? They have to be, yes they are bc if you are replicating and some rate but your cells are dividing, you will not complete replication What would happen in microtubules were disrupted during the cell cycle If you disrupt microtubules and cannot pull the chromosomes apart, you will be unable to separate chromosomes into daughter cells What would happen if each chromosome failed to replicate and produce 2 sister chromatids? Rather than maintain the same amount of genetic information in the daughter cells you will simply cut it in half. What would be the effect of having the process of recombination take place during mitosis? You would become a mosaic of different genotypes What would be the result if meiosis 2 was eliminated? You will not go through the reduction phase, so later on during fertilization, the next embryo will be tetraploid rather than diploid, which would be lethal Why do histones interact with DNA at the minor grooves? Because there is very little DNA interactions going on, it’s a great place for charge
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27 jan 2010 molbio - Mol bio lecture notes 27 January 2010...

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