Exam 1 & Key - Spring 2009 MPP 3202

Exam 1 & Key - Spring 2009 MPP 3202 -...

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Unformatted text preview: FEB—24—EEEB 12:59 HEHLTH SCIENCE LIBRHRY 5738841421 P.81/12 flip-W UNIVERSITY OF MISSOURI 3529‘? (1 --?-0?) 1®®®0® s®©0®® 11$®®0® 1s.@@@@ 21®o@@@ aa@@@ww 2®®0@@ 7.®®@© 12®®@0@ 17®®0©® 22®@@o@ 27®©0¢1 3®®O®© a®l®®© 13®®O®@ 1a®®®l® 23$®®®O 23®l®flm 4®®Q®@ 90®®©© 140®®®® 19®0®®® 24®0@@@ 29@®@m1 5®I®®® 1o.@@@@ 15®®@I® 20®®I®@ 25®0®®© 390®©11 .um_________________u_______mm_m____________m_ ml®®®® 36®®®I® 41®®®O® 460®@@@ 51®®©®® 56$®®$$ fl®0@@@ 37®O@®@ 42®®I®@ 47®@@0@ 52®®®®® 57®®®W® m®®0®® as®®®0® 4s®¢®®® 43$®®O© 53®®®®® 58®®@@@ M®I®®® ss®®i®© 440®®®® 49@@0®@ 54®®©®® 59$®®Wfi fi®0@@® 4ul®®@@ 45®I@@@ 50.®@@@ 55@@@@@ eo®@@fia ________________________.u__________________.mm s1®®®®® ss®®®®® 71®®©®© 76®®®®® a1®®®®® as®®®w 62®®@@® sv®®©®® 72$®®®© 77©®®®© 82®®@@@ B7®®©L 63 CD®®®® BB ®®®€D® 73 CD®®®® 7a ®®®®® 83 CD®®®© BB ®®C331T3=§> 11- m@@@@@ as®®®®© 74®®©®® 79®®®©® a4®®®®© aa®®©12 B5®®®®© 70®®®®© 75@®@@@ an®®®®® as®®®®® 90®®©1u .______________m______________________mflmm.mw. 91®@@@@ 96 @®@®@ 101 b®®®® 106 @@@®@ 111 @@@®@ 116 ®®@:S§-ii“z M®@®®@ 97®®®®© m2@®®@@ m7®©©®® n2®®©®® n7®©©ym m®®©®© 93®®©®® ws@@@@@ ma®®®®® H3®®®®® H36®®Hfi M®®©®© 99®®@@@ m4@@@@@ wa®®®®® n4®®®®® n9®®®1~ 95®®©®© 100 ®®Ca3®© 11:15 @®@@® 110 ®®®®© 115 ®®@®® 120 @®@ 19%: m—mn—m 1m®®®®® us®®©®® m1@®@@@ u6@®@®@ m1®®®®® ma®®®¢w 1n®®®®® m7®®®®® m2@®@@© m7®®®®® u2@@@@@ n7®®®wm 1n®®®®© ma®®®®® w3@®®@@ ma®®®®® ma®®@@@ ma®®©®1 124®®<§3®© 129 ®@@@® 134 QD®©®© 139 ®®@@® 144 CD®®®® 149 (131319154 :Lié'i': 125®®®®<§D 130 ©®®®® 14o ®®@®@ 145 CD®®®® 150 CD®®<§11137532 us®®@@@ l—Izti—d-fil—dlfllfl‘j 13: Elli] H|:H|_ | H 23L, 1 IZNLJ: |_ 1 HHHHT D'KJtitE-fillfildl . I”: Eld/ 1d ? Phym' ' 3202-“? ' . ._ - my " '. ' - lat Exam, ss'og, Hayes: :1 News swam: Number "[TAmrlabmblemnnber) - __ .' ‘ LabDay ~ «i, o, l_. your name, student fiumber, TA (or lab tablo‘number) and lab doy and time above”. ‘ , ‘ - . _ 2. Oath: front. ofthe answer shoot print'yom' Homo, today’s date, your TA’s mm: (or in]: tablepmnbwhndyourlabdayandtflnm. ' ’. . ~ ‘ _ . o. 'Ffll infill: oori'esponfi .10 YDHI‘MIHB- Followa .dfitecfions fixingyom last. I . 4. Fill mom correspond toryour student mnnbot. You noodlnot fillin any. other 5. Onthebaokéftheansfiorahoetfiflifitheoiroletbat oqrrospondstothoono', ‘l answerto ouch-question. - -‘ . ' - .. '6._A15‘u www.marannmtmimo 7 ' IMEW-youro'mmandamworshoot ' Resultswm-befioswaabomnoofitommwonthebuneiinbomooutsiaethe'lab' . - .- Indonthooomse wob sitelmder'libraty Services”. keywfllbe Pofladinthesameplaooswhénaflstudontshflvotakontho'em ' - - w FEEl-Eél-EE’IE’IE' 13llZlE’l HEFILTH SCIENCE LIBRFIRY 5738841421 REE/12 1. What is physiology? It is the studyofthe structure ofthe body. Itisthe study cfthe chemicals ofthc body. It is the study of the efi'ects of disease on the body. It is the study of how the parts of the body work. :P'P’E‘JT‘ Whichtermdescribe3 the ability ofthe bodytomaintainaconstantinternal environment? l“ Positive feedback control Poaitive and negative feedback control Homeostasis Isostatic control :b-WNI—I- ' 32" HoW"iS'a'nbg'afive feedback'oofitfol'system best described? 1. Such Systems are found only rarely in the body.. . .. .2. It helPS ".21. f . _ '. .. ._‘_ . ff. :3: . . 3. Acbange inone variable causes eventsthattendtoremrnthatvariableto its original value. ‘ ' 4. A change in one variable‘causes' events that hiduce further changes in that variable. 4. What do cholesterol and phospholipids have in common? Both are ampbipathic. . .- Both are readily soluble-in plasma.“ ‘ - - Both are components of the plasma membrane. Both are derivatives of glycerol. saw— What is a starch? f" It is a polymer of amino acids joined by covalent bonds. .mhbfinamimmwfiamnsfimnmwwhmMMmamommam ... ..n_ It is the predomth storage form of carbohydrates in animals. It is an important su'uotlnal carbohydrate in plants. sym— btfi—d4—dflflfl fl} Ufltq F- :4 P'P‘E‘JE" fhtu thd b0 10. :F‘P’E‘JI“ lfiiflfl HtHLIH bthNLt LlfiHHHT Drdfifi4l4dl Which class of Compounds centains the greatest number of peptide bonds? Carbohydrates Lipids Proteins Nucleic acids Which class of compounds are usedprimarily as energy sources? Carbohydrates Lipids Proteins Nucleic acids How would one best describe a chemical bond formed when two atoms share an electron pair unequally? It is a non-polar bond and the compound will be practically insoluble in water. It is a polar bond and the compound will be readily soluble in water. It _is an ionic bond and the compound will be readilysoluble in I It is a polar bond and the compound will have little solubility in water. What are the principal fiinctions of cholesterol? It is a component of the plasma membrane and the precursor of all the steroid hormones. It is an important energy-yielding substrate and a component of the plasma membrane. It is the precursor of all the steroidlhormones a. of lipids.“ I It is a storage form of lipids and an energy-yielding substrate. What do fibroblasts, adipocytes (fiat cells), bone cells and blood cells have in common? They are all connective tissue cells. They all produce and secrete proteins. They are-all epithelial cells.- a -- - ~ w- ~ a They are all derived fi'om fibroblasts. F.U4/1d l‘tlj—dfil—dlfllfl‘j 1.3:: Ell HI:H|_ | H 23'... l IZNLJ: |_ l HHHHT D'KJtiti-fillfildl l" . Elb/ 1d \ 11. What kind of cells are produced as the fertilized egg (zygote) multiplies? 1. Cells ofthe fetal part ofthe placenta 2. Cells of the chorionic and amniotic membranes 3. Pluripotent stem cells 4. All the above are produced as the zygote multiplies. Match the cellular ctg'eit'el'ie (petitions 12:1 4)"'i't'ri'th‘ its 145). Questions 12. Ribosomes 13. Nucleus 14. Golgi apparatus Answers 1. Site of protein processing 2. Site ofATP Synthesis . ...3. .‘ Site ofiDNA'sttl'i‘ag'elantlTe'plicfitifinfi. l. .‘.. .' .1:.__;....::;":::_:::_2:33;...1:_: . i 4. Site of protein synthesis 5. Site offatty acid synthesis 15. What is the principal filnction ofDNA'? 1. It replicates for cell division. ‘ 2. It directs synthesis of messenger RNA (mRNA). 3. It connolstheprhnarysn-uetm-eofprotems. ‘ ‘ a -‘ 16. How do most non-polar enter and leave cells? 1. They cross the plasma membrane by simple diflilsion. 2. They are actively transported using energy. 3. They difl'use through protein channels in the plasmsmembrane. .4. Theycross the .plasmamembranebybindingmshepolscpansotphesphclipids. ..__ htfi—d4—dflflfl lfiifll HtHLIH bthNLt LlHHHHT DYJHH414£1 17. Which of the following will NOT increase the rate of simple difi'usion across the plasma membrane? 1. Increasing the temperature 2. Increasing the concentration gradient 3. Increasing the size of diffusing compounds 4. Increasing the non-polar character of diffusing compounds '18. Why is diffusion not suitable for long distance communication in large organisms? 1. It requires too much energy. 2. Not all compounds are capable of diffusion. 3. Diffusion is accompanied by osmosis. 4. It takes too much time. 19. F acilitateddifihsion can occur in the absence of a concentration gradient but simPle difi'usion requires such a gradient. 20. On the left is showna two compartment system at time 0. On the right is the same system some time later. Which statement best describes this system? 1. The membrane has a system for facilitated diflhsion of NaCl. 2. Simple difl'usion will account for the changes observed. 3. The membrane contains an active transport system for NaCl. 4- Ncaaatthaabqrssaaacsount_f9t.thashanses obscmd- . 5. Any of the shove could have produced the changes observed. 5" F.Ub/1d FEB-24-2EIIZIEI 13”le HEFILTH SCIENCE LIERFIRY 5738841421 REIT/12 21. What limits the entry of compounds into cells by facilitated diffusion? l. The amount of ATP available 2. The number-of channels 3. The solubility of compounds entering cells 4. The size of the channels 22. How is the Ca2+-ATPase pump best described? 1. It moves 2 Ca2+ ions out of the cell for each ATP used. 2. It is a component of the plasma membrane. 3. It maintains a low Ca2+ concenlration inside cells. 4. All the above describe the Ca2+-A'I'Pase pump. 23. Which of following describes the Na+-K-I-ATPase pump? 1. It moves 2 K.+ ions out of the cell and 3 Na+ ions into the cell for each ATP used. 2. It maintains a low K+ concentration inside cells. - It a -h_igh;Nc_+_-ccncccnaticn insidccclls. 4. 5. All the above It moves 3 Na+ ions out of the cell and 2 K+ ions into the cell for each ATP used. 24. Which of the following describes osmosis? 1. It is the active transport of water across the plasma membrane. 2. Water diffuses fi'om an area of lower non-penetrating solute concentration to an area of higher non-penetrating solute concentration. . ' '3: "Ions are-actively n'ansported acrossa membrane to equalize the concentration of ‘ water across that membrane. 4. 'Wate'r ditfnses from an area of higher non-penetrating solute concentration to an area of lower non-penetrating solute concentration. 25. The osmotic pressure within a cell is 300 mOsm/l. What will happen if the cell is exposed to a solution of 500 mOSm/l? l. The cellwill swell. 2. The cell will shrink. 3. The cell's volume will not change. 4. There are not enough data to predict. Ftfi—d4—dflflfl 26. :F-LI-Jll-Qt—I :h on Kiri 29. swwe 30. 1. 2. 13:61 HtHLIH bthNLt LlfiHHHT DYJUU414£1 According to Ohm’s Law, how will electrical current change if voltage and resistance are doubled? It will double. It will be reduced by half. It will be reduced by one quarter. It will not change. . What is calculated by the Nernst equation? The membrane potential of a cell at rest The current crossing the cell membrane during depolarization The electrical potential at which net movement of an ion by difiusion is stopped. The membrane potential at which a cell is most permeable to an ion. . What conclusion is supported by measurements showing that a cell’s resting membrane potential is —70mv and that the equilibrium potential for Hat is 59mv? Ilse diffusion otNa+ will be irrelevant to that cell’s iimction. .' The-cellhas ‘ir'erjt'low permeabilityto Na+. ‘ Calculation of the cell’s Na+ equilibrium potential will be inaccurate. Ohm’s Law will not apply to ions crossing the cell’s plasma membrane. How do changes in membrane potential take place in cells? The concentration of ions inside and outside of cells changes. The lipid bflayer of the plasma membrane becomes more polar. The threshold potential changes. I _ ‘ _ _l The permeability properties of the plasma membrane change. In an excitable cell the peak of a graded potential is always less than the threshold potential. True False F.UU/ld FEB-24-EEIIZI'3 13: IZIE HEFILTH SCIENCE |_ I BRFIRY STEEiEi-fiiléiEl F“ . Grill/12 For questions 31-33 answeritl ifthe statement describes agraded membrane potential, answer #2 if the statement describes an action potential and answer #3 if the statement describes both graded and action potentials. - 31. This potential varies witbthe strength ofthe stimulus. 32. This potential is due to the membranes reaching thresfiold‘ " 33. Hyperpolarization during this potential is due to increased permeability to K+. 34. Strong induce action potentials that have greater amplitude and duration than action potentials induced weaker stimuli. 1. True 2. False The figure below depicts changes in membrane voltage (Em) during an action potential. Questions 35-37 refer to this figure. WM'F'Cmsar-r) '35. [bring which part ofthe action potential is thecell’spcmleabflity tor Na-l-r" " ' greatest? 1. Part] 2. Part: 3. Part3 4. Part4 36. What. amethyst—tags; assistants K+ eh- " Iannels'?” ' 1. Thetansifionfi‘ompartltopartZ 2. 'l‘hetransitionfi-ompart2topart3 I 3. Thetrmsifionfi-omPartBtu-WA-ww--- a .. 4. ThereturntorestingmernbranepotentinlaflerparM. % Ftfi—d4—dflflfl 37. PPPI‘ 40. l. 3. 4. 41. 1'. 2. “"3T_ 4. ljifld HtHLIH bthNLt LlfiHHHT DYJUU414£1 What is caused by the closing of voltage—gated Na+ channels ? The transition from part 1 to part2 'I‘hetransitionfi‘ompartZtopartI-l The transition from part 3 to part 4 The retina to resting membrane potential afier part 4 . What best desciibes-the voltageagated Na+ channels are opening and closing then returning to their resting conformation? A greater than normal stimulus is required to depolarize the cell. The membrane’s voltage will be at its resting value. A less than normal stimulus will he suflicient to generate an action potential. An action potential cannot be generated no matter how strong the stimulus. . How do the somatic-land Monomie nervous systems difl’er? . The somatic nervous system is part of the central nervous system but the autonomic nervous system is not. " The seismic intervene-- system is an afi'erent-Isysternrthe autonomic nervous system is an efferent system. The somatic nervous system inmervates skeletal muscle; the autonomic nervous system mnervams a greater variety of tissues. Which part of a neuron generates only graded potentials? The dendrites Seenent ' The axon H a in . The nerve terminal Which type of neuron will have the slowest rate of action potemial conduction? A large diameter, myelinated neuron A large diameter, unmyelinted neuron -AsnraH-diameter-mye}inated--neuren-a—--——- ‘- - A small-diameter, unmyelinatedneuron F.16/ld FEB-24—EEEE‘ 13: IZIE HEFILTH SCIENCE |_ I BRFIRY 5738841421 P . 1 1/ 12 42. Howls a chemical synapse best described? 1. Itprovidesforthedireetpassage ofions fiomone cellto another. . 2. It is the fastest way in which one cell communicates with another. 3. It requires release ofanem'otransmitter, its hindingtoarcceptor. 4. It is anartiflctduetothcmethodsusedtoprepsretissuesformicrosoopy. 43. What is a'gapjunctiou? l. ItisthespaecbetWeeneeflsacrosswhichancuronansmitterdifl'uses. 2. Itisasn'uchn'ethatjoinstwocellssoionscanmovefi'omonecelltotheother. 3. It formswhensecrctory (synaptic) vesiclesfiisewiththeplastnamembmne dining neurotransmitter release. 4. It is a channel in the plasma membrane through which ions enter the cell from outside. 44. A cholinergic receptor issue which binds acetylcholine and is the receptor which, when occupied, stimulates skeletal muscle cells. 1.1.! . T1116 : :‘ . ...i'.".'._.. :2: '_‘.:‘.i' '. .'_“ L. . . . .gi. 2. False 45. At the neuromnsclllarjtmetlon many end plate potentials are required to induce an action potential in a skeletal muscle cell. 1. True 2. False -- "46. In the central nervous system-many excitutory-post—synaptic potentials (EPSPs) are an. action potential in the post-synaptic neuron. 1. True 2. False FEB-24-EBEE 47. l. 48. seer 50. 13=E2 HEHLTH SCIENCE LIBRHRY 5738841421 Which statement is INCORRECT? Neurotransmitters in the central nervous system can stimulate or inhibit post- synaptic cells but at the netu‘omuscular junction a neurotransmitter only stimulates. Neurons in the central nervous system are innervated by many other neurons but at the nenromuscnlar junction a muscle cell is innervated by a single neuron. . There are many neurotransmitters in the central nervous system but only one at the neuromuscular junction. In both the central nervous system and at the neuromuscular junction post- synaptic cells are directly stimulated via gap junctions. What is the way in which inputs and outputs are integrated in the central nervous system? is a corresponding output. If afferent input is stimulating, efferent output will also stimulate; if it’s inhibitory, output will also inhibit. corresponds to a stimulus. Spatial and temporal summation determine whether or not stimulating and inhibiting inputs depolarize the neuron innervated. . How is acetylcholine cleared from a synapse? It diffuses away. It is taken up by the cell that secreted it. It seamstress enzym" uneasy." " ” It is taken up by the post synaptic cell. To get this answer right, fill in circle 1. // P.12/12 . Central nervous system nexuons are innervated unease—one so for each input there i " .m'7‘Eff'erent‘sigiials are matched to afl'erent signals so that'airewonse always ‘ ' " ' TDTHL P.12 ...
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This note was uploaded on 02/17/2012 for the course MPP 3202 taught by Professor Hurley during the Spring '08 term at Missouri (Mizzou).

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Exam 1 &amp;amp; Key - Spring 2009 MPP 3202 -...

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