Exam 3- Winter 2003 MPP3202

Exam 3- Winter 2003 MPP3202 - DCT-El-EEEE 89:34 HEHLTH...

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Unformatted text preview: DCT-El-EEEE 89:34 HEHLTH SCIENCE LIBRHRY 5738841421 P.81/29 Student name: A n m _ _ m_________i_ Student number: _ TA name: Thurs/Fri ELEMENTS OF PHYS IQLDGY 3rd Examination April 8, 2003 Fill in the top of the question sheet and answeer sheet. Include your TA‘s name and lab day on the question sheet. We only need your name and TA‘s name on the top to the answer sheet. You don't need to fill any circles on the front page. Circle the letter of the answer that best completes the statement on the question sheet and fill in the appropriate answer circle on the answer sheet. Each answer is worth 2 points unless otherwise indicated. Turn in both the question and answer sheet. Staple the answer sheet to the back of the question sheet with the answer circles facing the back. Where in the nephron do diuretics act to increase urine formation? A. proximal convoluted tubule B. proximal convoluted tubule and loop of Henle C. proximal and distal convoluted tubules D. distal convoluted tubule and collecting duct Which of the body's fluid compartments contains the greatest volume of water? A. intracellular fluid B. extracellular fluid C. interstitial fluid D. plasma Which of the following is NOT a function of the kidney? A. regulation of body fluid volume and composition B. maintenance of acid—base balance C. excretion of metabolic waste products D. excretion of foreign materials like drugs and toxins E. All the above are functions of the kidney. Which body fluid compartment is characterized by a lack of significant protein content? A intracellular fluid B. interetitial fluid C plasma D None of the above lack protein. Page 1 DCT—Bl—EBBE Bfii34 5. HEHLTH SCIENCE LIERHRT STEEE41421 F.82/Bfi What fraction of the fluid filtered at the glomerulus is eventually excreted as urine? A. about 1% B. about 10% C. about 25% D. about 50% What is the significance of the fact that the afferent arteriole of a nephron has a greater diameter than the efferent arteriole? A. This arrangement prevents excessive loss of fluid from the capillaries in the glomerulus. B. This arrangement provides a constant glomerular filtration rate despite changes in mean arterial blood pressure. C. This arrangement increases capillary blood pressure in the glomerulus and increases filtration. D. This arrangement reduces pressure in the peritubular capillaries and increases reabsorption there. E. Both C and D are true. When the sympathetic nervous system is activated how is renal function changed? A. Glomerular filtration rate is increased and reabsorption by peritubular capillaries declines so urine volume rises. B. There is an increased secretion of renin which increases K+ secretion by distal tubules to increase urine volume. C. Renin secretion increases and vascular smooth muscle constricts to reduce glomerular filtration rate and urine volume. D. Sympathetic innervation of the kidneys is very sparse and it has little effect on renal function. Which statement best describes reabsorption of materials from the proximal convoluted tubule into peritubular capillaries? A. It is a passive process driven by osmotic and hydrostatic pressure differences. B. It accounts for about 10% of the total material reabsorbed from the nephron. C. It is regulated primarily by antidiuretic hormone and sympathetic innervation. D. It is accomplished by combining Na+-linked cotransporters, facilitated diffusion and osmosis. What are the mean arterial pressure (MAP) and the pulse pressure (PP) when systolic pressure is 120 mmHg and diastolic pressure is 90 mmHg? A. MAP e 100 mm Hg; PP = 30 mm Hg B. MAP = 100 mm Hg; PP = 210 mm Hg C. MAP = 105 mm Hg; PP e 30 mm Hg D. MAP = 105 mm Hg: PP = 210 mm Hg Page 2 DCT—Sl—EBBS 89:34 10. ll. 12. 13. 14. 15. HEHLTH SCIENCE LIBRHRY 5738841421 P.83/89 Which of the following provide for constant renal blood flow and glomerular filtration rate over a wide range of mean arterial blood pressure? vasoconstriction with changes in flow (myogenic control) vasoconstriction due to secretion of paracrine factors by A. Changes in E. Changes in epithelial cells. C. Changes in the level of activation of the sympathetic nervous system. D. All the above contribute to constant blood flow and glomerular filtration. Which of the following stimulates secretion of aldosterone? high K+ concentration in plasma low Na+ concentration in plasma an increase in renin secretion all the above incrrease aldosterone secretion. U n w W Under what conditions will glomerular filtration rate equal the plasma clearance of a solute? A. The glcmerular filtration rate is always equal to the plasma clearance. B. When the solute is neither secreted or reabsorbed by the renal tubules. C. When renal blood flow and glomerular filtration rate change to the same extent. D. When reabsorpticn falls below 95%. Which statement best describes renin? A. It converts angiotensinogen to angiotensin I, the precursor of a potent vasoconstrictor. B. It increases Na+ secretion in the distal tubule and collecting duct. C. It stimulates the movement of water out of the distal tubule and colelcting duct. D. All the above describe renin. Where does 90% of tubular reabsorption occur? in the in the in the . in the glomerulus proximal tubule and loop of Henle loop of Henle and distal tubule distal tubule and collecting duct U U w W What is the principal action of antidiuretic hormone? A. It stimulates renin secretion. B. It augments myogenic control of renal blood flow. C. It increases the number of water channels in the collecting duct to conserve water. D. It promotes loss of Na+ in the urine (natriuresis). Page 3 DCT—Sl—EBBS BE” 35 16. 17. 13. 19. HEHLTH SCIENCE LIBRHRY 5738841421 P.o4/oa Which of the following will occur in response to significant blood loss? A. Antidiuretic hormone (ADH) secretion will increase. B. Secretion of renin will increase. C. Production of urine will decline. D. All the above will be involved. The figure below is a typical lead II from an electrocardiogram. What accounts for most of the length of the P-Q interval? R Fm Mrs RVAL. atrioventricular (AV) node conduction B. sinoatrial (SA) node depolarization Purkinje fiber conduction D. atrial repolarization A pharmaceutical company is characterizing a new drug (X) in part. infusing it into test animals and measuring its concentrations in plasma and urine. The following results were obtained: by Concentrations of Compound X in plasma and urine Plasma (mg/ml) Urine (mg/ml) 50 0 100 0 150 20 200 70 250 120 Which conclusion is best supported by these data? A. The concentrations of X in plasma and urine are unrelated. B. The renal threshold of X is between 101 and 150 mg/ml of plasma. C. Plasma clearance of x is greater than its glomerular filtration rate. D. None of those conclusions is justified. Under what conditions do we perceive "white" light i.e. color? light with no A. When rod cells and cone cells are equally stimulated. B. When no cone cells are stimulated. C. When cone cells are equally stimulated. D. When rod cells are equally stimulated. Page 4 DCT=3I=EEEE _E9=35 ___HEHLTH SCIENCE LIBRHRY 5738841421 P.85/BS 20. What is the primary stimulus for secretio of atrial natriuretic peptide (AMP)? A. stretch of the right atrial wall due to excess blood volume B. low flow in the distal convoluted tubule at the juxtaglomerular apparatus C. an increase in plasma osmolarity D. any of the above will stimulate ANP secretion Match the vessel type with its appropriate characteristic. pressure conduit expand and recoil under high pressure exchange substances between blood and cells regulation of blood pressure Contain one—way valves HUGH?” 21. Veins 22. Arterioles 23. Capillaries 24. Aorta 25. Small arteries 26. The hearbeat is initiated by the CNS the conducting system in the heart, which includes the Senode. the sympathetic nervous system the sysmpathetic and parasympathetic nervous systems U 0 w W 27. The cause of the pacemaker potential in SA node cells is: A. spontaneous increase in SA membrane permeability to Ca2+ due to opening of voltage gate L—type Ca2* channels. B. spontaneous increase in SA membrane permeability to Na+. C. spontaneous increase in SA membrane permeability to K+. D. spontaneous increased in SA membrane permeability to Cl‘. 28. What is the cause of repolarization in all the excitable cells (i.e., neurons, skeletal muscle, cardiac muscle, a SA node cells) discussed in Physiology 201? A. increased permeability for Na+. B. decreased permeability for K+. C. increased permeability for K+ by opening voltage—gated K+ channels. D. 'increased permeability for Ca2+ by opening Lntype Ca2+ channels. Page 5 DCT-El-EEEE 89:35 HEHLTH SCIENCE LIBRHRY 5738841421 P.86/BB 29. Tetraethylammonia (TEA) is a molecule that blocks voltageugated K+ channels. What will happen to the action potential of a myocardial contractile cell (i.e, cardiac myocyte) if TEA is applied to it? A. The myocyte will repolarize much slower. E. The myccyte will not depolarize and will not contract. C. The myocyte will spontaneously hyperpolarize. D. The action potential will be unchanged from normal. 30. The absolute refractory period in cardiac muscle is A. shorter than the absolute refractory period in skeletal muscle B. the same length of time as the absolute refractory period in skeletal muscle C. longer than the absolute refractory period in skeletal muscle D. important in determining quantal summation in the heart 31. In excitation—contraction coupling, the calcium that causes the contraction comes from the opening of A. voltage-sensitive calcium channels in the sarcoplasmic reticulum B. calcium—sensitive channels in the sarcoplasmic reticulum that have picked up calcium from the extracellular fluid C. the T—tubules binding all available calcium D. calmcdulin binding of calcium 32. AV valves open and close because of A. nervous impulses. B. contractions of muscles attached to the valves. C. changes in blood pressure in the adjacent chambers and/or blood vessels. D. contractions of fibers attached to the valves. 33. During ventriuclar filling, pressure is greatest in which of following: A. aorta E. left ventricle C. left atrium D. vena cava 34. During blood ejection, pressure is greatest in which of following: A. aorta B. left ventricle C. left atrium D. vena cava 35. The amount of blood remaining in the heart after contraction is the A, end—diastolic volume B. end-systolic volume C isovolumetric ventricular relaxation volume D stroke volume Page 6 DCT—El—EBBS @9336 HEHLTH SCIENCE LIBRHRY 5738841421 P.87/BB 36. Stroke volume increases when: A. there is an increase in afterload. B. there is greater calcium concentration in cardiac myocytes in response to sympathetic innervation. C. there is a decrease in end-diastolic volume. D there is an increase in total peripheral resistance. 37. The reason that cardiac muscle does not undergo quantal summation (i.e., recruitment} is: A. The presence of gap junctions between myocytes, which causes all myocytes to contract in near synchrony. B. Myocytes have a long refractory period. C. Myocytes are striated muscle. D. Trigger Ca2+ causes Ca2+ release from the sarcoplasmic reticulum. 33. The primary reason that a cardiac myocyte cannot be tetanized is: It has intercalated discs that contain gap junctions. It is striated. It has a single nucleus and considerable mitochondria. its long refractory period U D w W 39. A person with a heart rate of 60 heats/minute and a stroke volume of 85 ml will have a cardiac output of A. 51.1 L/min s. 3.06 L/min C. 510 ml/min D. 5.1 L/min 40. Which one of the following is not a factor in determining the flow rate of blood in a partiCular vessel? A. viscosity of the blood in the vessel B. length of the blood vessel C. radius of the vessel D. thickness of the vessel wall 41. Decreasing the radius of a blood vessel twofold will increase the resistance to blood flow A. sixteen fold B. four fold C. eight fold D. two fold For questions 42—48 characterize the cardiovascular changes during moderate exercise for each of the following as A - increase B e decrease C — no change 42. blood flow to brain? Page 7 LIL | —.jl—dfl|d.j we: fit! HI:HI_ | H bthNLI: LIHHHHT D'I’Jtiti-fil-lfil-dl |—'. Elti/U‘j 43. blood flow to viscera 44. blood flow to skin 45. end-diastolic volume 46. stroke volume 47. total peripheral resistance 48. With exercise venous return increases. Which of the following factors is not involved with increasng venous return? A. vasodiltion of skeletal muscle arterioles B. increased depth and rate of respiration skeletal muscle contraction increase in mean arterial blood pressure all of the above assist in returning blood to the heart (i.e., venous return.) [EDD 49. The principal force that causes fluid to move from the capillary to the interstial fluid is the: A. tissue pressure B. plasma oncotic (protein osmotic) pressure C. capillary hydrostatic (blood) pressure D. tissue osmotic pressure 50. Which of the following would not result in tissue edema? A. an increase in protein concentration of the plasma B. an increase in the pore size of systemic capillaries C. blockage of lymph vessels D. a decrease in protein concentration of the plasma Page 8 LIL | —Jl—dfllfilj 21:1: db HI:HI_ | H bthNLI: LIHHHHT D'I’Jtiti-fil-lfil-dl |—'. H‘j/U‘j Answer Key for Test "w03exam3.tst", 4/6/2003 NO. in ND. an Q-Bqng‘ Test Corrgpthnswe; 16 111 1 D 16 112 2 A 16 113 3 E 16 114 4 B 16 115 5 A 16 116 6 E 16 117 7 C 16 118 8 D 16 119 9 A 16 120 10 D 16 121 11 D 16 122 12 B 16 123 13 A 16 124 14 B 16 125 15 c 16 126 16 D 16 127 17 A 16 128 18 B 16 129 19 C 16 130 26 A 14 149 21 e 14 150 22 D 14 151 23 C 14 152 24 B 14 153 25 A 14 154 26 B 14 155 27 B 14 157 28 c 14 158 29 A 14 159 30 C 14 160 31 B 14 161 32 c 14 162 33 A 14 163 34 B 14 164 35 B 14 165 36 B 14 166 37 A 14 167 38 D 14 168 39 D 14 169 40 D 14 170 41 A 14 171 42 c 14 172 43 B 14 173 44 A 14 174 45 A 14 175 46 A 14 176 47 B 14 17B 48 E 14 179 49 C 14 180 50 A Page 1 TDTHL P.89 ...
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This note was uploaded on 02/17/2012 for the course MPP 3202 taught by Professor Hurley during the Spring '08 term at Missouri (Mizzou).

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Exam 3- Winter 2003 MPP3202 - DCT-El-EEEE 89:34 HEHLTH...

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