NOTES ON MPTP AND PARKINSONISM

NOTES ON MPTP AND PARKINSONISM - NOTES ON MPTP AND...

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NOTES ON MPTP AND PARKINSONISM The video clip shown in class was broadcast in July of 1993 and described the mysterious outbreak in California in 1982. One day seven young people were admitted to the hospital and were unable to walk or to speak. It was quickly learned that they were OK only a day or two before so their illness was a complete mystery. These people were reportedly “turned to stone” and were quite rigid. On the third day in the hospital someone put a pad of paper in front of one and placed a pencil in his hand. He wrote “I don’t know why or what has happened to me.” He was asked if he had taken any drugs and he wrote down heroin. One doctor remarked that these patients seemed to have suffered a severe case of Parkinson’s disease, but since they were so young that did not seem possible. When they were given the drug l-Dopa they began to recover immediately and could walk and talk, an outcome which suggested Parkinson’s. They had purchased on the street a chemical which they believed to be a synthetic heroin. Some investigation found that this drug was being made by a young basement chemist who on his last batch must have made a mistake. He tried to make the drug MPPP, but instead made a drug now known at MPTP. When the drug was first analyzed by authorities it did not match the
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This note was uploaded on 02/20/2012 for the course PSY 223 taught by Professor Charleskutscher during the Spring '12 term at Syracuse.

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NOTES ON MPTP AND PARKINSONISM - NOTES ON MPTP AND...

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