452_NA_structures

452_NA_structures - MAJOR GROOVE IN THE FORM OF H-BOND...

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Biochemistry 452 Nucleic Acids Structures Study Guide bold=questions Dr. Ninfa has asked on exams for last 10 years. 1. Difference between syn and anti. 2. Sugar puckers seen in nucleic acids. 3. What is a DNAseI footprinting experiment and what does it show? 4. DRAW THE STRUCTURES OF THE BASE PAIRS FOUND IN DNA AND SHOW HOW UNAMBIGUOUS SEQUENCE INFORMATION IS OBSERVED IN
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Unformatted text preview: MAJOR GROOVE IN THE FORM OF H-BOND ACCEPTORS AND DONORS, METHYL GROUPS, AND A RING H ATOM. 5. Provide 2 examples of H-bonding betwen amino acid side chains and base pairs in the major groove. (Structures). 6. What is direct readout and indirect readout?...
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