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Unformatted text preview: Learning Issue BUN/Creatinine Erica Young Note: GFR was found in many of the references I used. Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the tiny filters in the kidneys, called glomeruli, each minute. The tests for kidney function is another learning issue, so I didnt want to cover it. This learning issue I provided a MD consult definition and then provided my own simple explanation. If this is not formal enough, confuses others, and does not help others I will not do it in the future. Blood Urea Nitrogen Urea is continuously formed by the metabolism of ammonia in the liver. Hepatic deamination implies the splitting off of amide (-NH 2 ) groups from amino acids, and their conversion to ammonia, which enters the arginine cycle and is converted to urea. Urea nitrogen is a small, uncharged molecule, not protein bound, that is rapidly cleared from the blood by glomerular filtration. It subsequently undergoes reabsorption by the tubules so the blood urea nitrogen filtration....
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- Fall '10