LIDIMETAPP.docx - Learning Issue Dimetapp Name Gina...

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Learning Issue: Dimetapp Name: Gina Hendricks Acetaminophen ; Brompheniramine ; Dextromethorphan ; Pseudoephedrine Dimetapp® Childrens Nighttime Flu Classification: Analgesics Antihistamines H 1 -blockers Sedating H 1 -blockers Autonomic Agents Sympathomimetics Adrenergic agonists Respiratory Agents Adrenergic agonists Decongestants Respiratory Agents Antitussives Description: Acetaminophen, brompheniramine, dextromethorphan, and pseudoephedrine are used together in an oral preparation for the temporary relief of symptoms due to the common cold or flu. Some products are also marketed for the temporary relief of symptoms of allergic rhinitis or other upper respiratory allergies. Specifically, these products are used to relieve rhinorrhea, sneezing, watery and itchy eyes, coughing, nasal congestion, sore throat, headache, body aches, and fever. Acetaminophen is an antipyretic and a non-narcotic analgesic; its analgesic effect may be produced by a direct action on the pain threshold due to inhibition of prostaglandin synthesis. Its analgesic activity may also be related to inhibition of the synthesis or actions of chemical mediators or other substances that sensitize pain receptors to mechanical or chemical stimulation. Brompheniramine is an H1-receptor antagonist that dries nasal and sinus passages secondary to its anticholinergic activity. Brompheniramine usually causes less sedation than diphenhydramine. Dextromethorphan is a centrally acting cough suppressant used to inhibit dry, nonproductive coughs. Dextromethorphan decreases the sensitivity of cough receptors or interrupts the transmission of cough impulses by depressing medullary centers of the brain. Pseudoephedrine is a sympathomimetic agent that stimulates alpha1-adrenergic receptors in
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.

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LIDIMETAPP.docx - Learning Issue Dimetapp Name Gina...

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