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atrial fibrillation - Learning Issue Atrial Fibrillation...

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Learning Issue: Atrial Fibrillation Name: Michael Holmes efinition Atrial fibrillation (AF) is a supraventricular tachyarrhythmia characterized by disorganized atrial electrical activity and progressive deterioration of atrial electromechanical function. Atrial fibrillation is the most common arrhythmia encountered in clinical practice and is a significant public health problem in the United States. Atrial fibrillation affects more than 2.2 million Americans and almost 5% of the population older than 69 years. The prevalence of atrial fibrillation increases dramatically with age. Atrial fibrillation is associated with known cardiovascular risk factors such as hypertension, coronary artery and valvular heart disease, heart failure (HF) and diabetes mellitus. In addition to Risk factors: •Hemodynamic stress •Atrial ischemia. •Inflammation •Drug use •Endocrine disorders •Neurologic •Familial atrial fibrillation
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Factors Risk Factors Risk Prior stroke or TIA History of hypertension Heart failure and/or reduced left ventricular function Advanced age Diabetes Coronary artery disease athophysi While the precise mechanisms that cause atrial fibrillation are incompletely understood, atrial fibrillation appears to require both an initiating event and a permissive atrial substrate. Significant discoveries in the last decade
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