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Unformatted text preview: tissue ATP levels, and an accumulation of catabolites, including those of the adenine nucleotide pool. As ischemia continues, tissue acidosis develops and there is an efflux of potassium into the extracellular space. Subsequently, ATP levels fall below those required to maintain critical membrane function, resulting in the onset of myocyte death. Source: http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-4106-1. .50051-0--cesec68&isbn=978-1-4160-4106-1&sid=1080535386&type=bookPage&sectionEid=4-u1.0-B978-1-4160-4106-1. .50051-0--cesec68&uniqId=225850941-6#4-u1.0-B978-1-4160-4106-1..50051-0--cesec68...
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- Fall '10