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Mitral valve prolapse - Learning Issue Mitral valve...

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Learning Issue: Mitral valve Prolapse (auscultation) Type and Detection Findings on Exam Description Heard at the apex and left lower sternal border; easily missed in supine position; also listen with patient upright. Typically late systolic murmur preceded by midsystolic clicks, but both murmur and clicks highly variable in intensity and timing. Valve is competent in early systole but prolapse into atrium later in systole; may become progressively severe, resulting in a holosystolic murmur; often concurrent with pectus Source : Siedel HM, Ball JW, Dins JE, Flynn JA, Solmon BS, Stewart, RW. Mosby’s Guide to Physical Examination . 7th ed.: Mosby, Inc.; 2011: 408. Learning Issue: Mitral valve prolapse · · Definition: Is the most common valvular abnormality, affecting 2-6% of the population in the united states. · Causes: Usually occurs as an isolated entity. It commonly occurs with heritable disorders of connective tissue. MVP has also been described in association with a secundm atrial septal defect. · Risk Factors or Predisposing Factors: Commonly occurs with tissue disorders such as Marfan syndrome, Ehlers-Danlos syndrome, osteogenisis imperfect, and pseudoxanthoma elasticum. · Epidemiology: Is thought to be inherited with increased expression of the gene in females 2:1. The most common form is autosomal dominant, but X-linked inheritance has been decribed.
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  • Fall '10
  • Garrubba
  • Marfan syndrome, MVP, mitral valve, Mitral valve prolapse, Mitral regurgitation, severe mitral regurgitation

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