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Unformatted text preview: matrix constituents that come in contact with adherent platelets (e.g. collagen, vWF). Activated platelets undergo the release reaction, which they secrete contents that further promote aggregation and inhibit naturally anti-coagulant endothelial cell factors. During platelet aggregation (platelet-platelet interaction), additional platelets are recruited from the circulation of the site of vascular injury, leading to the formation of an occlusive thrombus. The platelet plug is anchored and stabilized by the developing fibrin mesh....
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.
- Fall '10