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Furosemide - Template completed by Furosemide-MH DeloneTM |...

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Template completed by: Furosemide-MH Delone™ | Furosemide | Lasix® CLASS Cardiovascular agent-Diuretic Electrolytic and Renal Agent-Loop Diuretic DESCRIPTION (basic summary) Furosemide is a sulfonamide-derived loop diuretic used in the management of edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome. Other uses include mild to moderate hypertension and as an adjunct in hypertensive crisis and acute pulmonary edema MECHANISM OF ACTION Furosemide is a loop diuretic that inhibits sodium and chloride resorption by competing with chloride for the Na+/K+/2Cl- co-transporter in the ascending limb of the loop of Henle A profound diuresis results from the increased urinary excretion of sodium, chloride, potassium, and hydrogen ions. In addition, furosemide increases the excretion of calcium, magnesium, bicarbonate, ammonium, and phosphate PHARMOKINETICS Furosemide is administered orally and intravenously.It is
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