HSVII.doc - Learning Issue: HSV II Name: Lindsay Francis...

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Learning Issue: HSV II Name: Lindsay Francis Definition A strain of the herpes simplex virus, a host adapted pathogen that causes a wide variety of disease. HSV II is associated w/ genital disease, but a lesion of the HSV II type can be found anywhere. Causes HSV viral infection. Spread by contact of mucus membranes, open sores, saliva Risk Factors It’s ubiquitous: HSV-I: by age 30, 50% of people in high SES and 80% of people with low SES have it. HSV II: Prevalence increases with increased sexual activity. Race: Black: 45% Mexican: 22% White: 17% Sex: Women 25% Men: 17% Pathophysiology HSV (1 &2) are double stranded DNA viruses that are characterized by the ability to colonize and reproduce in the nervous system, periods of latency and reactivation in an area relating to the branch/section of the nervous system that the virus invaded. Generally, the disease resides in/reproduces in a specific ganglia, to which it seems to be limited (unless there is inoculation and infection in the zones maintained by other ganglia). When stimulated (fever, trauma, stress, sunlight, menstruation), the disease reactivates, resulting in manifestation of sores and HSV shedding. Immunocomprimised individuals have reactivation more often
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.

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HSVII.doc - Learning Issue: HSV II Name: Lindsay Francis...

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