Migraine LO - Learning Issue: Migraine-MH (Learning...

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Learning Issue: Migraine-MH (Learning Objective) · Definition: Usually a pulsatile headache, which is usually unilateral. It commonly is accompanied by nausea, vomiting, photophobia, and phonophobia. Transient neurological symptoms, commonly visual, precede headache of classic migraines. No preceding aura is common. · Causes: May be linked to family hx of migraines. Attacks may be triggered from by emotional or physical stress, lack or excess sleep, missed meals, specific foods (chocolate), alcoholic beverages, bright lights, loud noises, menstruation, or use of oral contraceptives. · Pathophysiology: Possibly related to neurovascular dysfunction. A headache is stimulated by dilation of blood vessels innervated by the trigeminal nerve as a result of released neuropeptides from the parasympathetic nerve fibers approximating these vessels. The probable underlining mechanism is the activation of the trigeminal nerve nucleus caudalis, nucleus tractus solitarius, and dorsal raphe nucleus. · Signs & Symptoms:
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.

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