psychotic drugs - PsychDrugs Drug Class Drug Example...

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Psych Drugs Drug Class Drug Example Method of Action Side Effects indication Barbiturates D2 antagonist (dopamine antagonist) blocks 5HT2 (serotonin) and D4 recepter Tricyclics anxiousness, insomnia, impotence depression, panic disorders, OCD hypertensive crisis, sedation blocks reuptake of serotonin and norepinephrine no known side effects depression, nerve pain (fibromyalgia) bipolar disorder anti-epileptics see below seizures: T-C, CP, SP seizures: T-C, CP, SP; trigeminal neuralgia seizures: T-C, CP, SP seizures: A, M, T-C, SP, CP seizures: A seizures: A, AT, M; panic disorder Benzodiazepin es alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan) binds to receptor, increases time of chloride influx, depolarizes post-synaptic cell, prevents post- synaptic cell depolarization, increases GABA binding/affinity CNS depression, dependence, abrupt withdrawal may induce seizures generalized anxiety disorder, panic disorder, panic attack phenobarbitol, amobarbital, pentobarbital, thiopental binds to receptor, increases time of chloride influx, depolarizes post-synaptic cell, prevents post- synaptic cell depolarization, increases GABA binding/affinity CNS depression, dependence, smaller therapeutic window insomnia, seizure disorders, induction of anesthesia Typical Antipsychotics (old) haloperidol (Haldol), chlorpromazine (Thorazine), fluphenazine, thioridazine sedation, tardive dyskinesia, dystonia, Parkinsonism, orthostatic hypotension schizophrenia-positive symptoms, chemo- related nausea Atypical
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