TineaPedis.docx - LO: Tinea Pedis Natalie Koler 4-13-11...

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LO: Tinea Pedis Natalie Koler 4-13-11 Tinea Pedis: -A dermatophyte infection of the soles of the feet and between the digits -aka “Athlete’s foot” -Most commonly caused by Trichophyton rubrum Nondermaphyte causes include Candida species -Epidemiology: -World’s most common dermatophytosis -70% of population will be infected at some point -Affects males > females -Most cases occur after puberty; rare in children -Pathophysiology: -Dermaphyte fungi invade the superficial keratin of the skin & remains limited to this layer -Dermaphyte cell walls contain mannans that inhibit the body’s immune response -T. rubrum especially contains mannans that reduce keratinocyte proliferation causing a decreased rate in sloughing state of infection -Host factors such as abrasions or breaks in the skin may aid in dermaphyte invasion -Signs & Symptoms: -Pruritic, scaly soles & often painful fissures btw the toes -Less often complain of vesicular or ulcerative lesions
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TineaPedis.docx - LO: Tinea Pedis Natalie Koler 4-13-11...

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