anaphylaxis - I was doing this learning issue, when I saw...

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I was doing this learning issue, when I saw it was previously done by Nicole M from the same source I was using. So I read it to confirm and added a few things. Our guy DEFINITELY has it, no? Anaphylaxis MEDICAL EMERGENCY! Definition - an acute multiorgan system reaction, potentially fatal, caused by the release of chemical mediators from mast cells and basophils - classic form involves prior sensitization to an allergen with later re-exposure, producing symptoms via an immunologic mechanism - but anaphylaxis has no universally accepted clinical definition it’s a clinical diagnosis based on typical systemic manifestations, often with a history of acute exposure to a causative agent Causes Depends on what you are allergic to but common ones include. . -foods (ex. peanuts, shellfish) - parenteral antibiotics (e.g. penicillins, cephalosporins) and other oral meds - hymenoptera stings (i.e. bees, wasps, hornets, ants) - IV contrast materials - can also be idiopathic Risk Factors/ Predisposing Factors - atopic disease (e.g. allergic rhinitis, asthma, atopic dermatitis) - pts with allergy to penicillins are more likely to have an allergy to cephalosporins also (esp. 1st generation) than pts who aren’t allergic to pencillin Epidemiology - allergic reactions to food cause 125 deaths/yr in the US - about 1 in 5000 exposures to a parenteral dose of penicillin or cephalosporin causes anaphylaxis
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.

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anaphylaxis - I was doing this learning issue, when I saw...

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