Peripheral Blood smear (tables)

Peripheral Blood smear (tables) - Learning Issue:...

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Learning Issue: Peripheral Blood Smear-MH Description: It is useful when a patient has an abnormal WBC count, platelet count with or without anemia, has a report of atypical WBC. The test gives information about the number and shape of blood cells. Indications: Anemia Thrombocytopenia Suspected blood disorder Cancer Hairy cell carcinoma Hemoglobinopathies Monitoring effects of chemotherapy TABLE 161-1 -- EXAMPLES OF WHEN REVIEW OF THE PERIPHERAL BLOOD SMEAR CAN AID IN DIAGNOSIS Diagnosis Peripheral Blood Smear Clue Pernicious anemia Hypersegmented neutrophils Acute leukemia Blasts, Auer rods Disseminated intravascular coagulation Fragmented erythrocytes Myelofibrosis/marrow replacement Teardrop-shaped erythrocytes, nucleated erythrocytes Malaria, babesiosis Characteristic erythrocyte inclusions Fungal/bacterial infections Granulocytes with cytoplasmic organisms Viral infections Reactive lymphocytes Lead poisoning Basophilic stippling of erythrocytes Abnormal results: Abnormality in the size, shape, color, or coating of red blood cells. Graded on 4 point scale. o 1+ means 25% of cells are affected o 2+ means half of cells are affected o 3+ means 75% of cells are affected o 4+ means all of the cells are affected TABLE 74-3 -- Differential Diagnosis of Microcytic Hypochromic Anemias by Laboratory Tests TEST IRON DEFICIENCY ANEMIA ANEMIA OF CHRONIC DISEASE THALASSEMIA MINOR SIDEROBLASTIC ANEMIA Peripheral blood smear Normocytic to microcytic hypochromic RBCs, pencil Normocytic to microcytic hypochromic RBC Normocytic to microcytic hypochromic RBC, target cells, Dimorphic RBCs (microcytic hypochromic and macrocytic),
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TEST IRON DEFICIENCY ANEMIA ANEMIA OF CHRONIC DISEASE THALASSEMIA MINOR SIDEROBLASTIC ANEMIA cells basophilic stippling basophilic stippling, Pappenheimer bodies RDW Increased Near normal Normal Increased Serum iron Reduced Reduced Normal to increased Normal to increased
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This note was uploaded on 02/18/2012 for the course PAS 600 - 601 taught by Professor Garrubba during the Fall '10 term at Chatham University.

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Peripheral Blood smear (tables) - Learning Issue:...

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