Chapter 7 Chem114A

Chapter 7 Chem114A - Structure of Macromolecules Proteins...

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Structure of Macromolecules • Proteins • Carbohydrates • Lipids • Nucleic Acids Wednesday, November 16, 2011
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Function follows structure By understanding protein structure, you learn a lot about protein function. For example, understanding the structure of hemoglobin allows us to understand why mutations in hemoglobin result in sickle-cell anemia (Chapter 7). Wednesday, November 16, 2011
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Protein Function • Hemoglobin (Chapter 7) • Enzymes (Chapter 8) • Catalysis (Chapter 9) • Regulation (Chapter 10) Wednesday, November 16, 2011
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How do proteins work? Wednesday, November 16, 2011
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Protein Functions • Structural • Binding • Catalysis • Switching Wednesday, November 16, 2011
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Binding Catalysis Switching Structural Wednesday, November 16, 2011
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Protein Functions • Structural (Chapter 2 and 3) • Binding (Chapter 7) • Catalysis (Chapter 8 and 9) • Switching (Chapter 10) Wednesday, November 16, 2011
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Structural Proteins Some structural proteins only form stable assemblies Proteins as frameworks, connectors and scaffolds Examples: keratin and actin Wednesday, November 16, 2011
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Binding Properties of Proteins Wednesday, November 16, 2011
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What is a ligand? What is a ligand-binding site? Wednesday, November 16, 2011
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Antibodies as a great example of the binding properties of proteins Wednesday, November 16, 2011
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Wednesday, November 16, 2011
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Wednesday, November 16, 2011
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Chapter 7 Chem114A - Structure of Macromolecules Proteins...

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