Chapter 9 Chem114A

Chapter 9 Chem114A - Enzymatic strategies Chapter 9 1...

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Enzymatic strategies Chapter 9 1. Covalent Catalysis 2. General Acid-Base Catalysis 3. Catalysis by Approximation 4. Metal Ion Catalysis 1 Sunday, November 20, 2011
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Examples of catalytic mechanisms Proteases (chymotrypsin) Carbonic Anhydrase Restriction Endonucleases (BamHI) Nucleoside monophosphate kinases (NMP kinase) 2 Sunday, November 20, 2011
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Examples of catalytic mechanisms Proteases (chymotrypsin) Carbonic Anhydrase Restriction Endonucleases (BamHI) Nucleoside monophosphate kinases (NMP kinase) 3 Sunday, November 20, 2011
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Disiopropylphophofuoridate (DIPF) Reacts with serine residues 6 Sunday, November 20, 2011
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Chymotrypsinogen is a precursor of chymotrypsin 10 Sunday, November 20, 2011
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Chapter 9 Chem114A - Enzymatic strategies Chapter 9 1...

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