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Unformatted text preview: The appearance of Fragile X Syndrome in a human being is directly correlated with the presence of a protein that lies on the long arm of the x chromosome called FMR-1 and the repeat of the CGG chain it contains. FMR-1 is officially or scientifically called Fragile X Mental Retardation 1 (FMR1). Although FMR-1 is frequently employed in many bodily tissues, the function of this protein is indefinite (Dieder). FMR-1 can be named as the culprit for Fragile X Syndrome because the extensive repetition of the CGG chain leads the methylation of the FMR-1 gene that concludes the silencing of the gene altogether, resulting in the full Fragile X mutation. Even though the protein’s function is unknown, FMR-1 is located in neurons at very high levels, but the same cannot be said for the neighboring glial cells which have a low level of the FMR-1 protein (Dieder). Glial, or neuralgia cells are non-neuronal cells that aid to sustain homeostasis within the neuro-cellular environment (“Glial Cell”). FMR1’s role in the brain is homeostasis within the neuro-cellular environment (“Glial Cell”)....
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This note was uploaded on 02/21/2012 for the course BIO 2450 taught by Professor Martin during the Spring '10 term at Texas State.
- Spring '10