1.12.12 ch 1 - 1/1000 of a gram Doses given in accordance...

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1.12.12 Psychology 503
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Announcements 1.12.12 Few more comments about class…
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What is a drug? How do we define a drug?
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What is a drug? How do we define a drug?
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Drug Names
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Example Drug 1 Structure Chemical Name 2,6-diisopropylphenol
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Example Drug 1 Generic or International Non-Proprietary Name (INN): Propofol Trade or Proprietary Name: Diprivan
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Example Drug 2 Structure Chemical Name (+)-( S )- N -Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-
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Example Drug 2 Generic Name : Duloxetine Proprietary Name : Cymbalta (Ariclaim , Xeristar , Yentreve , Duzela).
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Example Drug 3 Structure Chemical Name (+)-5-methyl-10,11- dihydro-5 H -dibenzo[ a , d ]cyclohepten-5,10-imine
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Example Drug 3 Generic Trade Name : Dizocilpine Commonly known by its letter/number code, MK-801. No Proprietary Name because it is an experimental drug . MK-801: Merk; 801st compound in a series of synthesis…
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Dosages Describing Doses Milligrams:
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Unformatted text preview: 1/1000 of a gram Doses given in accordance to body weight 1 mg/kg dose for human 270 lbs = 122.7 kg 122 mg dose Dose Response Curves Dosages and Dose Response Curves Describing Dosages ED50 The Median effective dose The dose that is effective in 50% of the subjects tested. LD50 Median lethal dose The dose that was lethal in 50% of the subjects tested. ED50 and LD50 Results of a hypothetical experiment using 12 groups. One curve shows the percentage of animals in each group that lost consciousness; the other curve shows the percentage that died at each dose. Potency and Effectiveness The extent of the drugs effect They do not mean the same thing. Potency Differences in the ED50 Effectiveness Differences in the maximum effect that drugs will produce at any dose. Potency and Effectiveness...
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This note was uploaded on 02/21/2012 for the course PYSC 503 taught by Professor Mr.harrod during the Spring '12 term at South Carolina.

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1.12.12 ch 1 - 1/1000 of a gram Doses given in accordance...

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