for Midterm Part 3

for Midterm Part 3 - HLA class I , as exemplified by the...

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Teleology ‘for the sake of some aim or goal’ related to orthogenesis
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Difference
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Millankovitch Cycles Orbital shape – 100 ky cycle Axial tilt – 41 ky cycle Axial precession – 26 ky cycle 41 ky 100 ky 26 ky
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axial precession orbital shape axial tilt calculated insolation
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Skull 6, Ngandong, Homo erectus
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On migrating Out-of-Africa modern humans encountered archaic humans, residents of Eurasia for more than 200ky and having immune systems better adapted to local pathogens ( 25 ). Such adaptations almost certainly involved changes in
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Unformatted text preview: HLA class I , as exemplified by the modern human populations who first colonized the Americas ( 17 , 18 ). For small migrating populations, admixture with archaic humans could restore HLA diversity following population bottleneck, and also provide a rapid way to acquire new, advantageous HLA variants already adapted to local pathogens. For example, HLA-A*11, an abundant archaic allotype in modern Asian populations, provides T cell-mediated protection against some strains of Epstein-Barr virus (EBV) ( Denisovans...
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This note was uploaded on 02/22/2012 for the course 070 111 taught by Professor Sielder during the Spring '08 term at Rutgers.

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for Midterm Part 3 - HLA class I , as exemplified by the...

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