22991 - The danger Numero Uno That's how it reaches you Unprotected sexual intercourse Intravenous drug abuse and shared needles From a HIV

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The danger Numero Uno
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That’s how it reaches you Unprotected sexual intercourse Intravenous drug abuse and shared needles From a HIV positive mother to her infant during breastfeeding
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No ,Not this way
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I am no less World Population is six billion Two billion have me The Tubercle Bacilli.
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Transmission and Pathogenesis Prospective cohort studies have documented high rates of TB (5-10% per year) among HIV infected populations, particularly injection drug users. Exogenous re infection with another strain of M. tuberculosis has been documented in patients with advanced HIV disease.
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The risk of TB has been estimated to be over 9 times greater in HIV positive compared with HIV negative persons who have a positive tuberculin test. Outbreaks of TB, including multi-drug resistant disease, have highlighted the speed with which HIV infected patients progress to active TB after recent infection with M. tuberculosis .
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Double Trouble HIV alters the pathogenesis and clinical presentation of TB. The frequency of extra pulmonary TB increases with low Cd4 (70% with less than 100 count) The clinical and radiographic presentation may be atypical.
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TB and HIV HIV positive patients with TB have a significantly higher mortality when compared to HIV negative cases. Delays in the diagnosis of TB have been associated with worse outcomes, so initiation of treatment as soon as TB is suspected is very important.
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TB and HIV While initial studies emphasized the impact of HIV on the natural progression of TB, recent studies have demonstrated that TB may alter the natural history of HIV disease. Viral load has been shown to increase in the setting of active TB and decrease with appropriate therapy. Furthermore, HIV patients with TB have been shown to die sooner and develop AIDS faster than HIV-1-infected controls without TB.
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When to Suspect All patients should be questioned regarding : close contact with a person who has MDR TB previous residence in a country where drug- resistant TB is common; previous treatment for TB, especially if it was incomplete; previous residence in an institution (e.g. prison, homeless shelter) with documented transmission of a drug-resistant strain of TB.
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Mantoux Screening Tuberculin skin testing should be done using the Mantoux method in all HIV patients. A tuberculin reaction of > 5 mm of indurations is classified as positive in persons known to have or suspected of having HIV infection.
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Mantoux Screening Unfortunately, as the CD4 lymphocyte count declines with progression of HIV , many patients no longer react to delayed-type hypersensitivity testing. More than 60% of persons with CD4 lymphocyte
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This note was uploaded on 02/22/2012 for the course HISTORY 308 taught by Professor St. john during the Spring '11 term at Rutgers.

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22991 - The danger Numero Uno That's how it reaches you Unprotected sexual intercourse Intravenous drug abuse and shared needles From a HIV

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