3781 - OutbreakofBotulism AssociatedwithFermented...

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Outbreak of Botulism  Associated with Fermented  Beaver – Alaska, 2001 Louisa Castrodale, DVM, MPH Section of Epidemiology Alaska Division of Public Health
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Outbreak Southwestern Alaska village 14 Alaska Natives Beaver paw and tail Lunchtime on January 17 Following morning, symptoms  compatible with botulism
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Botulism Ingestion of toxin produced by  Clostridium botulinum Blocks Ach release at neuromuscular  junctions Symmetrical descending paralysis Incubation 12-36 hrs (range 6-240) Case fatality rate 5-10%
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Symptoms GI, neurologic, respiratory Diagnostic Pentad Nausea or vomiting Dysphagia Diplopia Dilated, fixed pupils Dry throat
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Botulism in Alaska First outbreak in 1940s Highest rate in United States Case-patients all Alaska Natives Consuming traditional foods Recent decline coincident with  prevention efforts by AIP-CDC
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Interviews of exposed persons Symptoms and onset Food history
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3781 - OutbreakofBotulism AssociatedwithFermented...

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