25691 - Combating Infectious Diseases and the Disease...

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Unformatted text preview: Combating Infectious Diseases and the Disease Control Priorities Project: A Convergence of Epidemiology, Economics and Research World Bank Washington, D.C. November 8, 2006 Joel G. Breman, MD, DTPH Fogarty International Center National Institutes of Health Outline DCPP Objectives Burdens - Global- Infectious Diseases Malaria Case Study Intervention Cost-Effectiveness- Best Buys- One Million Dollars Main Messages Objectives of DCPP (1) To decrease illness, disability, death, and economic burden by: Developing an evidence base to inform decision-making by: Providing estimates of the cost-effectiveness and impact of single interventions and packages Collaborating in defining disease burdens globally and regionally Summarizing implementation experience in different regions and globally www.dcp2.org Objectives of DCPP (2) Communicating major findings “Best buys” and the “worst buys” Disseminating the results Stimulating national priority setting and program implementation www.dcp2.org Disease Burdens Deaths Disability-Adjusted Life Years Global Infectious Diseases Leading Causes of Death in High and Low-/Middle-Income Countries (LMICs), 2001 (Total = 56.24 million) High Income (% total deaths) (n =7.89 million (14%) 1. Ischemic heart disease (17.3) 2. Cerebrovascular disease (9.9) 3. Trachea, bronchus, lung cancer (5.8) 4. Lower respiratory infections (4.4) 5. Chronic obstructive pulmonary disease (3.8) LMICs (% total deaths) (n = 48.35 million (86%) 1. Ischemic heart disease (11.8) 2. Cerebrovascular disease (9.5) 3. Lower respiratory infections (7.0) 4. HIV/AIDS (5.3) 5. Perinatal conditions (5.1) Mathers et al., 2006, in Lopez et al, Global Burden of Disease and Risk Factors High Income (% total deaths) (n = 7.89 million (14%) 6. Colon and rectum cancers (3.3) 7. Alzheimer’s and other dementias (2.6) 8. Diabetes mellitus (2.6) 9. Breast cancer (2.0) 10. Stomach cancer (1.9) Total: 53.6% (ID = 4.4%) LMICs (% total deaths) (n = 48.35 million (86%) 6. Chronic obstructive pulmonary disease (4.9) 7. Diarrheal diseases (3.7) 8. Tuberculosis (3.3) 9. Malaria (2.5) 10. Road traffic accidents (2.2) Total: 55.3% (ID = 21.8%) Mathers et al., 2006, in Lopez et al, Global Burden of Disease and Risk Factors Leading Causes of Death in High and Low-/Middle-Income Countries (LMICs), 2001 Disability-Adjusted Life Years (DALYS) Burden of Disease on a Defined Population Aggregate of premature mortality, morbidity, and disability Adjustments made for life expectancy long-term disability (weighted) Valid indicator of population health Tied to effectiveness of interventions Disease Burden by Income, 2001...
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This note was uploaded on 02/22/2012 for the course HIST 312 taught by Professor Staff during the Fall '10 term at Rutgers.

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25691 - Combating Infectious Diseases and the Disease...

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