40281 - The Hepatitis C Virus Epidemic in Egypt Dr F...

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The Hepatitis C Virus Epidemic in Egypt Dr. F. DeWolfe Miller, FACE John A. Burns School of Medicine Department of Tropical Medicine, Medical Microbiology and Pharmacology U N I V E R S I T Y O F H A W A I ‘ I A T M Ā N O A Honolulu, Hawaii [email protected] HCV in Egypt Web Site
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F. DeWolfe Miller I am a tenured full professor of epidemiology and tropical medicine here at the University of Hawaii In 1972 I got a job at Pahlavi Medical School, Shiraz, Iran where I met Dr. Denis Burkett. In 1975 I moved to Cairo and for the next 4 years worked on the epidemiology of schistosomiasis and the impact of the Aswan High Dam. It turned out that the Dam had little if any impact on schistosomiasis epidemiology in Egypt. I continued off and on working and living in Egypt on schisotosomiasis and started the Schistosomiasis Research Project. During that time an Egyptian colleague and I discovered that 10% of the Egyptian blood supply was positive for HCV. In the meantime I had moved from the University of Michigan faculty to UH. In 2008 I had a senior Fulbright Fellowship to Egypt to work on the epidemiology and control of HCV. In August 2010 we published an estimate of HCV incidence in Egypt in PNAS
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Learning Objectives Learn about the hepatitis C virus (HCV) Learn the importance of HCV in Egypt Understand how the epidemic of HCV in Egypt was discovered Understand the uniqueness of this epidemic and the role of iatrogenic transmission. Learn about measures to reduce HCV transmission in Egypt
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Performance Objectives To be able to explain the HCV epidemic in Egypt to others Know and explain the routes of HCV transmission To be able to critically assess the epidemiologic literature published about this epidemic. Be able to devise public health measures to prevent HCV in Egypt
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HEPATITIS C VIRUS (HCV) THE VIRUS HCV is a small (50 nm in size), enveloped, single-stranded, positive sense (+ss)RNA virus Small even for viruses Classified in the family Flaviviridae (includes Yellow and Dengue fevers) Subdivided into 6 genotypes (1 – 6) which have specific geographic distributions The major genotype in Egypt is 4.
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HCV is a Blood borne pathogen Transmission of HCV from person to person is by blood: HCV is a Blood borne pathogen Mother to new borne transmission also occurs. Very little if any sexual transmission HCV has no known reservoir in animals HCV is found only in humans
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Discovery of HCV in Egypt The first HCV ELISA tests became available in Egypt in 1992. These kits were being donated by Abbot throughout Europe and the Middle East. Nothing at the time was known about the occurrence of HCV in Egypt. Dr. Moamena Kamel, Professor clinical
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This note was uploaded on 02/22/2012 for the course HIST 312 taught by Professor Staff during the Fall '10 term at Rutgers.

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40281 - The Hepatitis C Virus Epidemic in Egypt Dr F...

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