This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: translation occurs, viral particles formed. Innate immunity -HRV blocks interferon production (interferons stimulate transcription/translation of proteins to attack viruses ex. RNase)-HRV stimulates release of IL-10: Anti-inflammatory, blocks phagocytosis in macrophages Adaptive immunity-Lots of serotypes-antigens-Blocks dendritic cells (immune cells-process antigen material), prevents activation of T cells HRV slows T cells and thereby B cell activation, blocks phagocytosis, increases risk of bacterial infection. 5 cap, 3 poly-A tail ribosomes use initiators to start protein synthesis which recognize the 5 cap viral infection turns off the ability to recognize capped messages, thus viral genome is used Virus has to recognize cell then virus has to get inside the cell Defense Mechanism-HRV...
View Full Document
This note was uploaded on 02/20/2012 for the course CELL STRUC 301 taught by Professor Tepperman during the Spring '12 term at Ohio State.
- Spring '12