Biology 311C Lecture 12 - September 21, 2011 Biology 311C...

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September 21, 2011 Biology 311C Lecture 11 The cytoskeleton is a network of fibers extending throughout the cytoplasm. It organizes the cell’s structures and activities, anchoring many organelles. It is composed of three types of molecular structures: microtubules, microfilaments, and intermediate filaments. We should compare and contrast: structure of the three types (components, hollow?, size), function (movement?, tension?, compression?), location in cell (nucleus, cytoplasm), motor proteins (kynesin, myosin (interacting with inner filaments), dynein). The movement of RNA molecules form the nucleus to the cytoplasm is not involved in the cytoplasm in eukaryotic cells. The structure of microtubules are hollow tubes; wall consists of 13 columns of tubulin molecules. It has a diameter of 25 nm with 15-nm lumen. Its protein subunits are tubulin, a dimer consisting of alpha tubulin and beta tubulin. Its main functions include maintenance of cell shape, cell motility, chromosome
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