Biology 311C Lecture 16 - There is a predominant clinical...

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September 30, 2011 Biology 311C Lecture 16 Inside of a cell is negative. Na+ ions are higher outside the cell than inside. When passive Na+ channels open, Na+ ions move in, making the inside more positive. Cl- ion concentration is about the same inside and outside. Passive Cl- channels open so Cl- ions move out making the inside more positive. Cystic fibrosis is a recessive genetic disorder. It is a defective membrane function.
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Unformatted text preview: There is a predominant clinical problem in respiratory epithelium of lungs where mucus plugs block air flow. It also affects ducts in digestive tract in the pancreas. It requires physical therapy and antibiotic treatment. Cystic fibrosis is caused by a mutant CFTR protein. The cell cannot release Cl- ions; water is retained in the cell; mucus thickens....
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This note was uploaded on 02/21/2012 for the course BIO 311 C taught by Professor Mcclelland during the Fall '09 term at University of Texas at Austin.

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