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Biology 311C Lecture 16 - • There is a predominant...

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September 30, 2011 Biology 311C Lecture 16 Inside of a cell is negative. Na+ ions are higher outside the cell than inside. When passive Na+ channels open, Na+ ions move in, making the inside more positive. Cl- ion concentration is about the same inside and outside. Passive Cl- channels open so Cl- ions move out making the inside more positive. Cystic fibrosis is a recessive genetic disorder. It is a defective membrane function.
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Unformatted text preview: • There is a predominant clinical problem in respiratory epithelium of lungs where mucus plugs block air flow. • It also affects ducts in digestive tract in the pancreas. It requires physical therapy and antibiotic treatment. • Cystic fibrosis is caused by a mutant CFTR protein. The cell cannot release Cl- ions; water is retained in the cell; mucus thickens....
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