Unformatted text preview: relaxation. • binds to the active site of phosphodiesterase and inhibits it making it a competitive inhibitor. • In reception, binding of epinephrine to G protein-coupled receptor is present (1 molecule). • During transduction, it multiplies until it reaches one hundred million in the response. • The kinase is going to phosphorylate protein kinase A since it’s activated by cAMP. • The epinephrine is the first messenger is on the surface since the G protein-coupled receptor is at the plasma membrane. • Since the GTP is not attached to GDP, the G protein is always active and the water concentration is unbalanced. • 8.1, 8.2, and 8.3 and 55.3 need to be read....
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- Fall '09
- Viagra, protein-coupled receptor