BME300T1 - Ch.4 - Tissues, Glands, and Membranes Histology...

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Ch.4 - Tissues, Glands, and Membranes Histology – Microscopic study of tissues Recognizing normal and abnormal tissue Medically closely related to pathology and often used for definitive diagnosis of disease states Based on cell type Recognizing specific types of malignancy o Leukemia, Lung cancer Type lead to different prognosis/treatment Tissue Types 1. Epithelial 2. Connective 3. Muscle 4. Nerve Epithelial Covers internal and external surfaces Skin, lining of mouth intestines, ear canal Generally have free surface (reduces friction) and attach to underlying tissue through a basement membrane Diffusion must occur through basement membrane to or from Epithelial cells o Nutrients, oxygen , carbon dioxide HAS BASEMENT MEMBRANE, LITTLE EXTRACELLULAR MATERIAL, AND NO BLOOD VESSELS Functions 1. Mechanical protection
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a. Bottom of feet, burns, dehydration 2. Acts as barrier a. From water loss, toxic molecules, germs, etc. i. A break in epithelium leads to infection 3. Allows passage of some substances a. Oxygen, Carbon Dioxide i. Capillary Endothelium – allows water, nutrients to pass out of capillaries ii. In illness, Capillary permeability may increase and thus osmotic pressure decreases 1. Fluid loss out of vascular system iii. Pulmonary edema – Poor oxygen exchange due to a leak at capillaries in the lungs 4. Secretion of substances a. Sweat glands, mucous glands in respiratory epithelial layers, digestive system, enzyme-secreating portion of pancreas i. Endocrine – no ducts, secretes into blood ii. Exocrine – ducts, onto surface 5. Absorbing substances – ESPECIALLY IN INTESTINES Classification of Epithelia Classification by layer o Simple Epithelium – single layer cell o Stratified Epithelium – more than one layer of cells (some sit on top of other) Classification by shape o Squamous – scale like (flat) o Cuboidal – cube like o Columnar – tall and thin (Think columns!)
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1. Simple squamous epithelium
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This note was uploaded on 04/07/2008 for the course BME 300 taught by Professor Ab during the Spring '08 term at University of Tennessee.

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BME300T1 - Ch.4 - Tissues, Glands, and Membranes Histology...

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