Lecture13PopulationGenetics

Lecture13PopulationGenetics - become uniformno genetic...

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Chapter 13: Population Genetics Biology 301
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Genetic Variation or the Lack Thereof http://cacondorconservation.org/
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Genetic Variation Ultimate source is mutation Central Dogma of Molecular Biology Mutations = errors in DNA transfer Types—chapter 6 Microsattelites Genetic Markers PCR
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Maintenance of Genetic Variation Mutation Migration Environmental Variation Heterozygote Advantage, Frequency Dependent Selection
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Hardy-Weinberg Law 5 assumptions No evolution when in equilibrium Equations Know how to use/solve
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Inbreeding What assumption is broken by inbreeding?
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Inbreeding Non-random mating Assortative Mating: Positive or Negative Inbreeding Depression—2 examples in book Inbreeding Coefficient (F) – F=(H HWE -H Obs )/H HWWE
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Genetic Drift Results in loss of genetic variability Coalescence—average time is 4N generations In that time span, all copies of all genes
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Unformatted text preview: become uniformno genetic variabilityideal for lab experiments, but deadly in nature Founder eventsCattle egrets Population bottleneckCheetahs, elephant seals Effective population size (N e ) Genetic Variation Population growth and decline effects on genetic variation Large population size with low variability= recent population growth, or recent low population size Small population with high variability= recent population decline Loss of genetic variation by drift offset by migration and mutation Ecotypes offset by gene flow So Ends Exam 2 Material I will work on a review sheet of important concepts and skills to know Lecture on Tuesday will at least begin looking at species interactions, but I plan to save some time to answer questions about the exam...
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This note was uploaded on 02/23/2012 for the course BIOL E301 taught by Professor Mr.franklin during the Spring '12 term at South Carolina.

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Lecture13PopulationGenetics - become uniformno genetic...

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