37121 - Scope and Application of Stem Cell Research in...

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 Scope and Application of Stem Cell Research in  Livestock Jayanti Tokas 1 , Puneet Tokas 2 , Shailini Jain 3 , Hariom Yadav 3 1 Department of Biotechnology, JMIT, Radaur, Haryana, India 2 KITM, Kurukshetra, Haryana, India 3 NIDDK, National Institute of Health, Bethesda, MD 20892, USA Email:  yadavhariom@gmail.com  
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Stem Cell Stem cells are master cells with two important  characteristics Unspecialized cells capable of their own renewal Ability to differentiate  into different cell types The stem cells may have various differentiation  potentials Totipotent Pluripotent Multipotent Unipotent
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Types of stem cells Embryonic stem  cells Adult stem cells
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Characteristics of Embryonic stem cells Derived from ICM/epiblast of Blastocyst Pluripotent  Long-term  self-renewal Exibit and maintain a stable diploid normal complement  of chromosome Expression of Oct-4 Lacks G1 check point in the cells cycle Don’t show X inactivation
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Stemness  Genes Oct4 Nanog SSEA1 SSEA2 SSEA3 BMP4
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Characteristics of Adult stem cells Long-term  self-renewal Give rise to mature cells having characteristic  morphologies and specialized functions
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This note was uploaded on 02/23/2012 for the course AGRICULTUR 200 taught by Professor Staff during the Fall '11 term at Rutgers.

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37121 - Scope and Application of Stem Cell Research in...

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