# 34751 - Biostatistics course Part 14 Analysis of binary paired data Dr Sc Nicolas Padilla Raygoza Department of Nursing and Obstetrics Division

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Biostatistics course Part 14 Analysis of binary paired data Dr. Sc. Nicolas Padilla Raygoza Department of Nursing and Obstetrics Division Health Sciences and Engineering University of Guanajuato Campus Celaya-Salvatierra

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Biosketch Medical Doctor by University Autonomous of Guadalajara. Pediatrician by the Mexican Council of Certification on Pediatrics. Postgraduate Diploma on Epidemiology, London School of Hygiene and Tropical Medicine, University of London. Master Sciences with aim in Epidemiology, Atlantic International University. Doctorate Sciences with aim in Epidemiology, Atlantic International University. Associated Professor B, School of Nursing and Obstetrics of Celaya, university of Guanajuato. [email protected]
Competencies The reader will know how show paired binary data. He (she) will apply hypothesis test for paired binary data – McNemar’s Chi-squared. He (she) will calculate confidence interval for paired binary data. He (she) will obtain Odds Ratio and confidence interval for cases-controls paired studies.

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Introduction In Parts 12 and 13 of the biostatistics course, we knew, the methods for comparing two proportions estimated from independent samples. If the observations in a study are not independent, we need to use different methods. Often we use two types of studies that give rise to observations that are not independent: Repeated observations in the same individual Matched case-control studies
Example Tuberculosis can be diagnosed to use a culture media and looking if Mycobacterium tuberculosis is growing . In a experiment to compare two culture medias for the tuberculosis diagnosis, samples of expectoration from 100 patients were planted in the two medias. The half of the sample was planted in media A and another half of sample, planted in media B.

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Example In a study, to examine the relation between breast cancer and oral contraceptives, women with a breast cancer were matched with women without breast cancer, selected from electoral registries. This is an example of cases-controls study, where
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## This note was uploaded on 02/23/2012 for the course STAT 312 taught by Professor Staff during the Fall '11 term at Rutgers.

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34751 - Biostatistics course Part 14 Analysis of binary paired data Dr Sc Nicolas Padilla Raygoza Department of Nursing and Obstetrics Division

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