22441 - Energy Balance and Cancer Energy Balance and Cancer...

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Unformatted text preview: Energy Balance and Cancer Energy Balance and Cancer Survival Survival Michelle D. Holmes, MD, DrPH November 11, 2005 Cancer Survivorship • 62% 5 year survival over all adult cancers • 8.9 million US cancer survivors – 22% breast cancer (2 million) – 19% prostate cancer (1.7 million) – 11% colorectal cancer (1 million) Aziz; J Nutr 2002; 132: 3494S Topics • Energy balance (obesity, weight gain, activity) • Breast Cancer • Colon Cancer • Dietary fat and breast cancer Breast Cancer Energy Balance Obesity BMI kg/m 2 WHO definition Lbs, 5’4” <21 underweight <122 21-24.9 normal weight 122-144 25-29.9 Overweight 145-173 30-34.9 Obese 174-203 35-39.9 Severe obesity 204-231 ≥ 40 Morbid obesity ≥ 232 Source: Behavioral Risk Factor Surv eillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 198 5 No Dat a < 1 0% 10% –14% ( * B MI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” per son) Source: Behavioral Risk Factor Surveillance System , CDC. Obesity T rends* Amo ng U.S. Ad u lts BRFSS, 1 98 7 No Data < 1 0% 10%–14% ( * BMI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” person) Energy Balance Obesity 1985 vs. 1987 Source: Behavioral Risk Factor Surv eillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 198 5 No Dat a < 1 0% 10% –14% ( * B MI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” per son) Energy Balance Obesity 1985 vs. 1989 Source: Behavioral Risk Factor Surveillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 1989 No Data < 1 0% 10%–14% ( * BMI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” person) Source: Behavioral Risk Factor Surv eillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 198 5 No Dat a < 1 0% 10% –14% ( * B MI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” per son) Energy Balance Obesity 1985 vs. 1991 Source: Behavioral Risk Factor Surveillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 1 99 1 No Data < 1 0% 10%–14% 1 5% –19% ( * BMI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” person) Source: Behavioral Risk Factor Surv eillance System , CDC. Obesity Trends* Among U.S. Adults BRFSS, 198 5 No Dat a < 1 0% 10% –14% ( * B MI ≥30 , or ~ 3 0 lbs ove rw eight f or 5 ’ 4” per son) Energy Balance Obesity 1985 vs. 1993 Source: Behavioral Risk Factor Surveillance System , CDC....
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22441 - Energy Balance and Cancer Energy Balance and Cancer...

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