34021 - 2 nd overall leading cause of cancer death in the...

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Unformatted text preview: 2 nd overall leading cause of cancer death in the United States › 3 rd in each sex Approximately 6% of individuals in the US will develop a cancer of the colon or rectum within their lifetime 944,717 incident cases worldwide in 2000 Incidence rates for colorectal cancer differ by sub-sites Vast majority of colorectal cancers are adenocarcinomas, which are preceded by adenomas or adenomatous polyps in most cases Only around 10% of adenomas will develop into cancers, a process that takes at least 10 years 147,500 colorectal cancer cases in 2003 › 105,500 colon › 42,00 rectum 57,100 deaths from colorectal cancer Slight decreases in mortality rates since 1973 in both sexes Overall 5 year survival rate is 61.9% › Differs by race, age, and distribution of disease Survival rates are lower among than blacks than whites › 52.8% vs. 62.6% Survival rates are highest for localized cancers Incidence rates start to increase after age 35 with a rapid increase after age 50, when more than 90% of colorectal cancers develop...
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This note was uploaded on 02/23/2012 for the course SCI 310 taught by Professor Staff during the Fall '10 term at Rutgers.

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34021 - 2 nd overall leading cause of cancer death in the...

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