34111 - Primary liver cancer is the fifth most common...

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Unformatted text preview: Primary liver cancer is the fifth most common cancer in the world and the third most common cause of cancer mortality Hepatocellular carcinomas (HCCs) are malignant tumors of liver parenchymal cells 1.3% of estimated incident cancer cases are in the liver and intrahepatic bile duct Incidence rates are higher for males than females (2-4:1) Higher incidence for African Americans and Asians than whites 5 year survival rate is approximately 6.9% One of the most common malignancies in eastern Asia and sub-Saharan Africa Incidence up to 90.0/100,000 in some parts of the world More than 600,000 deaths in 2002 44% of the worlds cases occur in China Incidence increases with age then plateaus when the peak is reached, around 55 to 65 in the United States Ethnic and familial clustering have been reported Possible interaction between Hepatitis infection and a major gene Implicated as the probable cause of HCC in at least 80% of cases worldwide About 5% of the worlds population(350 million people) is chronically infected with HBV Lifetime risk of HCC for these individuals is estimated at 10-25% In low prevalence areas (such as the U.S.), is spread In low prevalence areas (such as the U....
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34111 - Primary liver cancer is the fifth most common...

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