34491 - UNIVERSITY OF PITTSBURGH CANCER INSTITUTE A...

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UNIVERSITY OF PITTSBURGH CANCER INSTITUTE A National Cancer Institute (NCI)-designated Comprehensive Cancer Center ةيمهأ ±ف ناطرسل² ³´ ةµاقو¶ل ةµول·¸² ءا¹عإ ناطرس¶ل ةيمµداك¸² زك²رمل² ºهأ نامربيه دلا±و² ²³تكدل´ غربستµ ةعماج ناطرسل´ د¶عم http://www.upmccancercenters.com ²´ذآ 2009
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بلغأ يف ة±راج²³ ثوح´²³ µذامن ¶اط·سل² ة¸م±داك¹³ زك³·م²³ : ىلع سيئر±ا زيكرت±ا ن²طر³±ا ´²جµع ¶ي³ح·و ر¸¹º· ¶طر³ت±ا ر»بم±ا ف²شتك¼ا ºأ ¶اط·س²³ ثº»¼ ع½م² ¾¸لق²³ ها´تن¿³ ÀÁº»¼ ·طاخ Ã ¾¸لقت²³
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ةحفاكمل ةيد±²قتل³ ةطشن´³ ل³ µف ¶ا·رسل³ ة±مي¸ا¹º³ ز¹³رم ¶ا·رس²ل ) 1 ( ةيحصلا ±²يحلا بيل²سا ³ف ث²ح´ا ريغ ±²يحلا بيل²سا نم µي¶قت¶ل ·²يجي¸ارتسا ةيحصلا ؛³حصلا ءاذ¹لا ؛ةض²ºرلا ؛نيخدتلا ةحف²كم ةº»ارحلا ·ارع¼لا ½¾هتسا نم µي¶قتلا ³ئºزجلا نطر¼تلا ث²ح´ا Molecular carcinogenesis   ( ) ةئي¿لا Àم ·²Áيجلا ·¾Â²Ã¸ ثودÄ رÅÆ´ ÇȲ¼¸ ³تلا ·²Áيجلا ةفرعم ·²É²طر¼لا
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ةحفاكمل ةيد±²قتل³ ةطشن´³ ل³ µف ¶ا·رسل³ ة±مي¸ا¹º³ ز¹³رم ¶ا·رس²ل ) 2 ( رطخلا ±ماوعل ةضرع²لا ت³´و²ج²لا صحف ةضرعلا µ³خش¶ل ةينيجلا ·¸و¹²لاº »نيجلا »نيجلا رطخ¼ل ةس³½¾º ·د¿دÀ ة¿وي¾ تÁÁ ر¿وطÃل ث³حبÁا ijÅر½¼ل ركƲلا ǹك¼ل ÈاوÉأ Ê´ ركƲلا ǹك¼ل ت³´و²ج²لا صحف ت³É³Åر½لا Êم ةنيعم
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يف مظعلا ر±ثأت²³ب ´وقµ ة¶³·و²ا ضار¸لا ن¸ د¶د¹²ا نرقلا يف ةم±علا ةحصلا يف تا²وط³لا ´ظµا 19 21 ة·دع¸لا ضارم¹ا ºم ة·±»ولا ¼½±ك ب¾س¿ ن±ك بÀقلا ضارما ىÀµ ´ظµ¹ا رÁثأ³لا ) ºÂ±³Ã Äا ة·¶Åا ىÀµ رÁ¾Æلا ı¾»¹ا statins ( رDZخ¸لا ÈÁÀق Éده¿ يف ذوخلا¶ ن±م¹ا ةمزÊË يñùا رÁثأ³لا ÌÅاوحلا ÈÁÀق رDZخ¸لا ÈÁÀق¶ ة·±»ولا ت±ÁجÁÂار³Ãا
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جذومنلا يطعت ب±قلا ضار²ا ة³´µولا ح´¶· ى±¸ ¹ث²ºا لا يف 30 تصق±ن² ة³ض±م´ا ةنس بµ¶´ا ·ار¸أ¹ ة¹±º»ا ب¼½ 50% ب¼¹ ¾±ك ¿ق±نÀ´ا Á¸ ة³ئ±قو´ا ةÂÃد»ا ل±معÀسا ت¸ÄخÀسا ة³ئاÃÄ´ا űساÆÄ´ا لÃرÀ¼´وÇ´اà طغÈ´ا ةÂÃدا Á³Âارش´ا ·ار¸ا ثÃÄح Éنم´ atherogenesis .
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This note was uploaded on 02/23/2012 for the course SCI 310 taught by Professor Staff during the Fall '10 term at Rutgers.

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34491 - UNIVERSITY OF PITTSBURGH CANCER INSTITUTE A...

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