1281 - Clinical Epidemiology Sense and Sensitivity Third...

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Unformatted text preview: . . , , Clinical Epidemiology: Sense and Sensitivity. Third Lecture Shai Linn, M.D. (Jerusalem), Dr.PH (Harvard) Head, Unit of Epidemiology Rambam Hospital and Faculty of Medicine, Technion, Israel [email protected] The Predictive Value . . - 2 ' - GOLD STANDARD S + S T + T- A C B D A+B C+D = SICKNESS : ; S+ . ST = TEST : T+ ; T S A+B C + D : Positive Predictive Value . A ---------A + B . , - " POSTTEST PROBABILITY OF DISEASE S+ T+ .P(S+|T+)- NEGATIVE PREDICTIVE VALUE - " NEGATIVE PREDICTIVE VALUE . D ---------C + D POSTTEST PROBABILITY OF NO DISEASE S- T- .P(S-|T- ) 1-D/(D+C) S + T- P(S+|T-) A/(A+B) + C/(C+D) P(S+|T) = P(S+|T+) + P(S+|T-) ...
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