7631 - Patterns of contraception in IDDM in the UK RA...

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Patterns of contraception in IDDM in the UK RA Lawrenson, GM Leydon, TJ Williams, RB Newson, MD Feher* Department of Epidemiology and Public Health, *Department of Clinical Pharmacology Imperial College School of Medicine
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Contraception in women with IDDM No UK studies No comparative studies Important to prevent unwanted pregnancies Risks of contraceptive use may have more serious consequencies in women with IDDM
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Oral contraceptive use Commonest method used in the UK Combined oral contraceptives with high doses of oestrogen may increase risk of cardiovascular disease and increase requirement for insulin CHD risk may be due to changes in lipids. New generation oral contarceptives (gestodene and desogestrel) seem to increase HDL and decrease LDL
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Oral contraceptive use (POPs) Progestogen only pills have less risk of cardiovascular problems. However they are less effective with 3 pregnancies per 100 women years of use Also have the problem of irregular bleeding
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Percentage of women by age using combined oral contraceptives for contraception 0 10 20 30 40 50 60 15- 19 20- 24 25- 29 30- 34 35- 39 40- 44 45- 49 No diab IDDM
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Percentage of women by age using third generation combined oral contraceptives 0 5 10 15 20 25 30 35 15- 19 20- 24 25- 29 30- 34 35- 39 40- 44 45- 49 No diab IDDM
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Percentage of women by age using second generation combined oral contraceptives 0 5 10 15 20 25 15- 19 20- 24 25- 29 30- 34 35- 39 40- 44 45- 49 No diab IDDM
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Preferential prescribing of third generation oral contraceptives ? Proportion of women with IDDM using a third generation oral contraceptive was 60% compared with 58% in women with no diabetes - OR 1.06 which was not statistically significant.
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Percentage of women by age using oral progestogen preparations for contraception 0 2 4 6 8 10 12 14 16 15- 19 20- 24 25- 29 30- 34 35- 39 40- 44 45- 49 No diab IDDM
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7631 - Patterns of contraception in IDDM in the UK RA...

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