15461 - Syphilis is still with us Paul R Earl Facultad de...

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Syphilis is still with us Syphilis is still with us Paul R. Earl Paul R. Earl Facultad de Ciencias Biológicas Universidad Autónoma de Nuevo León San Nicolás, NL, Mexico
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Syphilis is caused by the 5-15 micron spiral spirochete Treponema pallidum and is sexually transmitted. The bacterium spreads from the initial ulcer or chancre (shanker) of an infected person to the skin or mucous membranes of the genital area, mouth or anus of an uninfected sexual partner. In addition, a pregnant woman with syphilis can pass it to her unborn child, who may be born with serious mental and physical problems as a result of this infection: congenital syphilis.
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Primary syphilis involves chancre and regional lymphadenitis. Secondary syphilis usually involves generalized rash, mucous patches and condylomata lata. These 2 stages last about 12- 20 weeks and then syphilis becomes latent. During the first 2 years, the disease is called early syphilis. Pregnant women in hospital for maternity should be screened for syphilis, so that the result can be made available while they are still confined, and treatment can be provided if a positive diagnosis (seroreactive) is made. Their newborn infants should never be discharged from care until the mother's syphilis status is known.
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Primary and secondary syphilis rates*, by year - US, 1970-1997
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HEALTH MINIMUMS INCLUDE: ·Appropriate antibiotic therapy such as penicillin G ·Careful screening for other sexually- transmitted diseases (STD) ·Referral of partner(s) to a sexual health service for diagnosis, treatment and contact-tracing ·Instructions to refrain from sexual activity during treatment ·Regular follow up of immunological testing to ensure that titers steadily decline to low levels
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Elimination plans for sexualy transmissable diseases (STDs) have at least 5 strategies: - Increase surveillance. - Strengthen community involvement and partnerships. - Rapidly respond to outbreaks. - Improve and increase health promotion. - Expand clinical and laboratory services.
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IS THERE A HAPPY ENDING TO THE SYPHILIS STORY ? WILL NORWAY, CANADA AND THE US BECOME MILESTONES ON THE ROAD TOGLOBAL ERADICATION?
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Discovery Discovery “Everything” happened mostly in Germany from 1905 to 1910 ! With a short life of 35 years, Fritz Schaudinn (1871-1906) and Paul E. Hoffmann (1868-1959) discovered Treponema pallidum in serum in 1905. Paul Ehrlich, father of immunochemistry and his assistent Hati. Fritz Schaudinn  
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In 1903, Elie Metchnikoff (1849-1916) and Pierre Roux (1853-1937) found that syphilus can be transferred from man to chimpanzee and from one chimpanzee to another.
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In 1905, Aldo Castellani (1878-1971) discovered tropical yaws in children. August von Wassermann (1866-1925) and
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15461 - Syphilis is still with us Paul R Earl Facultad de...

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