17801 - CONSAGUINITY AND APNEA OF PREMATURITY Hala Tamim,...

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CONSAGUINITY AND  APNEA OF PREMATURITY Hala Tamim, PhD 1 Khalid Yunis, MD 2
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Background Definition of consanguinity  Consanguineous marriage is the union of  individuals having a common ancestor. It is  categorized as 1 st , 2 nd  and 3 rd  degree. The 1 st   being the closest kinship. It is believed that consanguineous  marriages would preserve: Family dynamics  economic benefits.
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  High estimates of consanguineous marriages  have been reported in various Arab countries: 54% in Kuwait 1 29-50% in Egypt 2 52% in Saudi Arabia 3 51% in the United Arab Emirates 4 50% in Jordan 5   15% in Lebanon 6 40% in Yemen 7 . Background Prevalence of Consanguinity
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Consanguineous marriages are more prevalent in rural than urban areas 8 , such marriages  have been positively associated with: Low age at marriage 8 , Low educational level of the  mother 9 , Low occupational status of husband 5 . Background Socio-demographic  Characteristics of Consanguinity
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Parental consanguinity increases the  autosomal recessive conditions through  the expression of recessive deleterious  alleles, especially in the offspring of  first degree cousins. Background Health Impacts of Consanguinity  
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Background Health Impacts of Consanguinity   Parental consanguinity has been associated with  increased risk of pediatric disorders including: Stillbirths and perinatal mortality 10 , Congenital birth  defects, Malformations, and mental retardation 11 Blood diseases (hemophilia, â-thalassemia) 12 cystic fibrosis 13 , Chronic renal failure 14  and  Neonatal diabetes mellitus 15 Cont’d
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Apnea of prematurity is a common problem in  the neonatal intensive care setting that affects 
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17801 - CONSAGUINITY AND APNEA OF PREMATURITY Hala Tamim,...

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