CN2010 Exam 2 - Cellular Neurobiology Biology 5571 Exam II...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Cellular Neurobiology Biology 5571 Exam II – Synaptic Physiology and Sensory Neurobiology November 9, 2010 Due Date - This exam is due at 10:30 in class, Thursday November 11. - You may also drop it off at my office before that (469 McDonnell Sciences- 4 th fl MSB). Sources - The exam is open book//open source, but you may not discuss it with anyone. - Please refer questions to me, or to any of the four lecturers Pages - Put your name at top of this page and put your NUMBER (top right) at the top of each page you submit. - Start each question on a new page - You can write on the pages provided or use your own blank sheets. - Don’t exceed page limits; limits assume use of double line spacing. - Show all your work – partial credit may be given. - Illegible answers will receive no credit. Point Distribution - The exam totals 100 points (Synapses 60 pts; Sensory 40 pts) Questions 1-2 10 pts ea. Questions 3 20 pts Questions 4-5 10 pts ea. Questions 6-7 8 pts ea Question 8 4 pts. Questions 9-10 8 pts ea Question 11 4 pts Question #1 (10 pts) (SM). (1/2 page) Synaptic physiologists have studied synapses that employ postsynaptic ligand-gated channels for many decades because the readout is (mostly) linear with respect to the amount of transmitter release. Discuss technical limitations and biological realities that limit the linearity between the amount of transmitter release and the size of the postsynaptic signal at glutamate synapses that employ AMPA receptors for transmission. Discuss both EPSP measurements and EPSC measurements. Consider baseline transmission only (not plasticity). When possible, suggest a way of overcoming the limitations with experimental manipulations or by choice of experimental preparation.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Question #2 (10 pts) (SM). (1/2 page) A small molecular buffer A for calcium has a binding rate constant for Ca
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/27/2012 for the course BIO 5571 taught by Professor P.taghert during the Fall '11 term at Washington University in St. Louis.

Page1 / 6

CN2010 Exam 2 - Cellular Neurobiology Biology 5571 Exam II...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online