CN2010 Membrane Physiology - Problem Set 1

CN2010 Membrane Physiology - Problem Set 1 - PROBLEM SET 1...

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PROBLEM SET 1 September 14 Due at start of class September 21 The problems are open book, but not collaborative. A key will be posted after lecture on the Tuesday the problems are due, so late submissions will not be accepted. These problem sets will replace in-class quizzes. Problem 1 Axon ion movements The squid axon has a specific membrane capacitance of 10 -6 Farads/cm 2 . The membrane potential is -60 mV at rest and +40 mV at the peak of the action potential. When the membrane potential changes, the charge on the membrane capacitance changes. A. 1. How many Na + ions must enter the axon per square centimeter of axon membrane to change the charge from the resting potential to the peak action potential? 2. How many K + ions must leave to return the potential to rest? B. 1. For an axon which is 400 μm in diameter, what is the surface area of a 1 cm length of axon? 2. How many Na + ions must enter the axon per centimeter of axon length to change the charge from the resting potential to the peak action potential? 3. How many K + ions must leave to return the potential to rest? C. 1. For an axon which is 400 μm in diameter, what is the volume of a 1 cm length of axon? 2. The intracellular ion concentrations for the squid axon are [Na + ] = 55 mM and [K + ] = 410 mM. What changes in the internal ion concentrations for Na
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CN2010 Membrane Physiology - Problem Set 1 - PROBLEM SET 1...

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